atypical antipsychotic

(redirected from Atypical neuroleptic)

atypical antipsychotic

A dibenzepine-type antipsychotic which differs from conventional antipsychotics in its paucity of extrapyramidal effects (tremor, muscle stiffness and restlessness).
Adverse effects
Insomnia, anxiety, agitation, sedation, dizziness, rhinitis, orthostatic hypotension, tachycardia, weight gain, menstrual disturbances, seizures; rarely, severe granulocytopaenia or agranulocytosis; should not be used in patients with liver, brain or circulatory defects.
Clozapine (Clozaril), ziprasidone (Geodon), loxapine (Loxitane), olanzapine (Zyprexa), resperidone (Risperdal), quetiapine (Seroquel).


(ant?i-si?kot'ik) [ anti- + psychotic]
1. Preventing or treating psychosis, e.g., schizophrenia.
2. A medication to treat psychosis.

atypical antipsychotic

Second-generation antipsychotic.

first-generation antipsychotic

A neuroleptic drug. They treat psychotic disorders and other psychiatric diseases. Side effects include extrapyramidal (Parkinsonian) reactions. Synonym: conventional antipsychotic See: neuroleptic (1)

conventional antipsychotic

First-generation antipsychotic.

second-generation antipsychotic

An antipsychotic drug that causes increased appetite, weight gain, and adverse effects on lipids. They differ from first-generation antipsychotics in that they are less likely to cause extrapyramidal side effects or tardive dyskinesia.
Synonym: atypical antipsychotic
References in periodicals archive ?
Clozapine was the first atypical neuroleptic to be developed, and has been used since the 1960s.
This quasi-longitudinal descriptive case study evaluated problem behavior for an adolescent boy with developmental disabilities via repeated functional behavioral analysis (FBA) probes during a blinded cross-over from the atypical neuroleptic Risperdal (Risperidone) to Seroquel (Quetiapine).
Atypical neuroleptic agents show benefit in studies for trauma-related psychotic symptoms such as hallucinations.
It rests on published findings from several short-term studies comparing one group of haloperidol-treated patients switched to placebo, with another group of haloperidol-treated patients switched to an atypical neuroleptic.
Husain suggested treating the patient initially with an atypical neuroleptic, then adding a cholinesterase inhibitor, and gradually tapering off the antipsychotic after several weeks.
In terms of consistent results, it seems that almost all atypical neuroleptics showed a high potential risk," Dr.
A case report published by Woolley and Smith (3) shows that atypical neuroleptics like Olanzapine and Amisulpride lower seizure threshold.
class of drugs called atypical neuroleptics has become commonly prescribed for schizophrenia, in part because they seem to improve problems like delusions, hallucinations and dementia linked with the neurodegenerative disease.
Association of diabetes mellitus with use of atypical neuroleptics in the treatment of schizophrenia.
In addition, all patients were treated with atypical neuroleptics and at least four medications to control behavior.

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