atypical antipsychotic

(redirected from Atypical neuroleptic)

atypical antipsychotic

A dibenzepine-type antipsychotic which differs from conventional antipsychotics in its paucity of extrapyramidal effects (tremor, muscle stiffness and restlessness).
 
Adverse effects
Insomnia, anxiety, agitation, sedation, dizziness, rhinitis, orthostatic hypotension, tachycardia, weight gain, menstrual disturbances, seizures; rarely, severe granulocytopaenia or agranulocytosis; should not be used in patients with liver, brain or circulatory defects.
 
Examples
Clozapine (Clozaril), ziprasidone (Geodon), loxapine (Loxitane), olanzapine (Zyprexa), resperidone (Risperdal), quetiapine (Seroquel).

antipsychotic

(ant?i-si?kot'ik) [ anti- + psychotic]
1. Preventing or treating psychosis, e.g., schizophrenia.
2. A medication to treat psychosis.

atypical antipsychotic

Second-generation antipsychotic.

first-generation antipsychotic

A neuroleptic drug. They treat psychotic disorders and other psychiatric diseases. Side effects include extrapyramidal (Parkinsonian) reactions. Synonym: conventional antipsychotic See: neuroleptic (1)

conventional antipsychotic

First-generation antipsychotic.

second-generation antipsychotic

An antipsychotic drug that causes increased appetite, weight gain, and adverse effects on lipids. They differ from first-generation antipsychotics in that they are less likely to cause extrapyramidal side effects or tardive dyskinesia.
Synonym: atypical antipsychotic
References in periodicals archive ?
Atypical neuroleptic malignant syndrome and atypical antipsychotics.
Cognitive impairment in schizophrenia and implications of atypical neuroleptic treatment, CNS Spect 1997; 2:1-11
Patients using atypical Neuroleptic, having prior episodes of NMS are considered at increased risk.
Atypical neuroleptic malignant syndrome: diagnosis controversies and considerations.
Clozapine was the first atypical neuroleptic to be developed, and has been used since the 1960s.
This quasi-longitudinal descriptive case study evaluated problem behavior for an adolescent boy with developmental disabilities via repeated functional behavioral analysis (FBA) probes during a blinded cross-over from the atypical neuroleptic Risperdal (Risperidone) to Seroquel (Quetiapine).
Atypical neuroleptic malignant syndrome presenting as fever of unknown origin in the elderly.
Atypical neuroleptic agents show benefit in studies for trauma-related psychotic symptoms such as hallucinations.
It rests on published findings from several short-term studies comparing one group of haloperidol-treated patients switched to placebo, with another group of haloperidol-treated patients switched to an atypical neuroleptic.
Early 1994 saw the introduction of another atypical neuroleptic, risperidone (Risperdal).

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