atovaquone


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atovaquone

 [ah-to´vah-kwōn]
an antibiotic used in treatment of mild to moderate Pneumocystis cariniipneumonia and the prevention and treatment of falciparum malaria; administered orally.

atovaquone

/ato·va·quone/ (ah-to´vah-kwōn) an antibiotic used in treatment of mild to moderate pneumonia and the prophylaxis and treatment of falciparum malaria.

atovaquone

(ə-tō′və-kwōn′)
n.
A drug, C22H19ClO3, used to treat pneumonia caused by pneumocystis fungi and, in combination with proguanil, to prevent or treat malaria.

atovaquone

[ah-to′vah-kwōn]
an antibiotic used in treatment of mild to moderate Pneumocystis pneumonia and the prevention and treatment of falciparum malaria. It is administered orally.

atovaquone

An agent used for treating mild to moderate Pneumocystis jiroveci (carinii) pneumonia in patients with HIV infection, and for salvage treatment of toxoplasmosis and microsporidiosis.
 
Pros
Less toxic, more tolerable than trimethoprim-sulfamethoxazole (TMP-SMX).

Cons
Less effective than TMP-SMX.
 
Adverse effects
Headache, nausea, diarrhoea, fever, rashes.

atovaquone

Mepron Infectious disease An agent used for treating PCP in Pts with HIV infection and for toxoplasmosis and microsporidiosis Pros Less toxic, more tolerable than T-S Cons Less effective than T-S Adverse effects Headache, nausea, diarrhea, fever and rashes. See AIDS, Pneumocystis cariniipneumonia, Trimethoprim–Sulfamethoxazole.

Atovaquone

A drug used in the treatment of MALARIA and TOXOPLASMOSIS. Brand names are Wellvone and, in combination with proguanil, Malarone.

atovaquone (ətō´vəkōn´),

n brand name: Mepron;
drug class: antipneumocystic;
action: unknown, may inhibit synthesis of ATP and nucleic acids;
uses: treatment of
Pneumocystis jiroveci (carinii) pneumonia in patients who are intolerant of trimethoprim-sulfamethoxazole.

atovaquone

a hydroxynaphthoquinone effective against protozoa; has been used in dogs to treat Pneumocystis infections and Toxoplasma tissue cysts.
References in periodicals archive ?
Some patients are extremely sensitive to the atovaquone and they do not have an allergy.
The data and the resulting findings concerning the mode of action of atovaquone could lead to improved medications against the tropical disease.
Mylan, a global generic and specialty pharmaceuticals company, has introduced Atovaquone and Proguanil Hydrochloride Tablets, 62.
M2 PHARMA-June 2, 2014-Mylan launches Atovaquone and Proguanil Hydrochloride Tablets
The evident increase in bioavailability of poor water soluble drug with fatty meal is base line in the design of lipid based formulations [4-6] and this was investigated and proved in case of many drugs like griseofulvin, halofantrine, danazol, atovaquone, and troglitazone [2].
Lapachol, although structurally related to Atovaquone, exhibits low activity against Plasmodium berghei in mice and against Plasmodium falciparum in vitro.
Adverse events associated with trimethoprim-sulfamethoxazole and atovaquone during the treatment of AIDSrelated Pneumocystis carinii pneumonia.
Acute Disseminated Fatal Toxoplasmosis After Haploidentical Stem Cell Transplantation Despite Atovaquone Prophylaxis in A Young Man.
falciparum in the lab to atovaquone or ELQ-300 and checked whether the parasite survived over eight weeks.
Type 2 Diarrhea Depression Diabetes Malaria Codeine Citalopram Repaglinide Atovaquone Phosphate Diphenoxylate Duloxetine Acarbose Sulfadoxine Steroid Budesonide Serotonin Metformin Pyrimethamine Reuptake Inhibitors Loperamide Repaglinide Artemether & Lumefantrine Metformin Amodiaquine Proguanil Malaron Atovaquone & Proguanil Diarrhea Diabetes Asthma Hypertension Codeine Glyburide Beclomethasone Propranolol Phosphate Dipropionate Diphenoxylate Intensive Ipratropium Angiotensin insulin Bromide Steroid Budesonide Enalapril Aminophylline Chlorthalidone Loperamide Insulin Isoprenaline Nisoldipine Repaglinide Salbutamol Hyperglycemia Angiotensin Hyperglycemia & Insulin
Treatment for cytauxzoonosis is usually imidocarb diproprionate, but a combination of atovaquone and azithromycin (A&A) has also been utilized as a treatment, (neither form of therapy has been prospectively evaluated for efficacy, however).