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Ativan |
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Ativan, trademark for a benzodiazepine antianxiety agent (lorazepam). lorazepam Apo-Lorazepam (CA), Ativan, Novo-Lorazem (CA), Nu-Loraz (CA) Pharmacologic class: Benzodiazepine Therapeutic class: Anxiolytic Controlled substance schedule IV Pregnancy risk category D ActionUnknown. Thought to depress CNS at limbic system and disrupt neurotransmission in reticular activating system. AvailabilityInjection: 2 mg/ml, 4 mg/ml Solution (concentrated): 2 mg/ml Tablets: 0.5 mg, 1 mg, 2 mg ⊘Indications and dosages ➣ Anxiety Adults: 2 to 3 mg P.O. daily in two or three divided doses. Maximum dosage is 10 mg daily. ➣ Insomnia Adults: 2 to 4 mg P.O. at bedtime ➣ Premedication before surgery (as antianxiety agent, sedative-hypnotic, or amnestic) Adults: 0.05 mg/kg (not to exceed 4 mg) deep I.M. injection at least 2 hours before surgery, or 0.044 mg/kg (not to exceed 2 mg) I.V. 15 to 20 minutes before surgery. For greater amnestic effect, give up to 0.05 mg/kg (not to exceed 4 mg) I.V. 15 to 20 minutes before surgery. ➣ Status epilepticus Adults: 4 mg I.V. given slowly (no faster than 2 mg/minute). If seizures continue or recur after 10 to 15 minutes, repeat dose. If seizure control isn't established after second dose, other measures should be used. Don't exceed 8 mg in 12 hours. Dosage adjustment• Elderly or debilitated patients Off-label uses• Acute alcohol withdrawal syndrome Contraindications• Hypersensitivity to drug, other benzodiazepines, polyethylene or propylene glycol, or benzyl alcohol PrecautionsUse cautiously in: Administration• For I.V. use, dilute with equal volume of compatible diluent, such as normal saline solution or dextrose 5% in water. Keep resuscitation equipment and oxygen at hand.
Adverse reactionsCNS: amnesia, agitation, ataxia, depression, disorientation, dizziness, drowsiness, headache, incoordination, asthenia CV (with too rapid I.V. administration): hypotension, bradycardia, tachycardia, apnea, cardiac arrest, cardiovascular collapse EENT: blurred vision, diplopia, nystagmus GI: nausea, abdominal discomfort Other: increased or decreased appetite InteractionsDrug-drug. CNS depressants (including antidepressants, antihistamines, benzodiazepines, sedative-hypnotics): additive CNS depression Hormonal contraceptives: increased lorazepam clearance Drug-herbs. Chamomile, hops, kava, skullcap, valerian: increased CNS depression Drug-behaviors. Alcohol use: increased CNS depression Smoking: increased metabolism and decreased efficacy of lorazepam Patient monitoring☞ During I.V. administration, monitor ECG and cardiovascular and respiratory status. Patient teaching• Tell patient and family about drug's possible CNS effects. Recommend appropriate safety precautions. Ativan® Lorazepam, see there How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Commonly prescribed and commonly abused by teens are Xanax (known as Zanies or Z bars), Valium, Ativan, and Klonopin. Drugs that have been associated with unintentional weight loss include selective serotonin reuptake inhibitors such as Paxil, Prozac, and Celexa; cardiac agents such as Lasix, Lanoxin, and Vascor; amphetamines; appetite suppressants such as Adderall, Dexedrine, Cylert, Meridia, and Ritalin; and benzodiazepines such as Ativan and Klonopin. The survey asked each plan for information about restrictions on five drugs: Advair, an asthma medication; Norvasc, a blood-pressure medication; Aciphex, a heartburn medication; Lexapro, an anti-depressant and anti-anxiety medication; and Ativan, another anti-anxiety medication. |
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