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astrocytosis |
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astrocytosis
[as′trōsītō′sis] Etymology: Gk, aster + kytos + osis, condition an increase in the number of neuroglial cells with fibrous or protoplasmic processes frequently observed in an irregular area adjacent to degenerative lesions, such as abscesses, certain brain neoplasms, and encephalomalacia. Astrocytosis represents a reparative process and in some cases may be diffuse in a large region. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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Hence, the reduced reactive astrocytosis in an injured segment of NRM-stimulated rats, as shown by reduced GFAP staining, could be directly related to the mechanisms of enhanced functional and anatomical restoration produced in the present experiments by NRM stimulation. Histopathologic examination of sections from the cortex, hippocampus, thalamus, hypothalamus, midbrain, pons, medulla, and cerebellum showed polioencephalitis affecting predominantly the diencephalon and brainstem and involving varying degrees of neuronopathy, neuronal loss, astrocytosis, parenchymal and perivascular lymphocytic infiltration with CD45 immunopositivity, sparse macrophage activation, and axonal spheroid formation. A classic triad of spongiform change, neuronal loss, and astrocytosis has been well described (figure 4). |
astrocytosis |
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