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protease
(redirected from Aspartic protease)

   Also found in: Encyclopedia, Wikipedia, Hutchinson 0.04 sec.
protease /pro·te·ase/ (pro´te-ās) endopeptidase.
pro·te·ase (prt-s, -z)
n.
Any of various enzymes, including the proteinases and peptidases, that catalyze the hydrolytic breakdown of proteins.

protease
[prō′tē·ās]
an enzyme that is a catalyst in the breakdown of peptide bonds that join the amino acids in a protein. See also proteolysis.

protease
any proteolytic enzyme.

protease-antiprotease imbalance
thought to play a part in the pathogenesis of emphysema by permitting excessive proteolysis, especially of elastin.
fecal protease
originate from the pancreas and include trypsin, chymotrypsin and carboxypeptidases. Proteolytic activity of the feces may be evaluated by tests that measure digestion of gelatin or casein-based substrates.
α1-protease inhibitor
α1-antitrypsin.


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We compared phenotypic markers of pathogenesis, including adherence, biofilm formation, and protein secretion (secretory aspartic protease [SAP] and phospholipase).
He applied these techniques to the design of compounds in a number of therapeutic areas, including aspartic protease inhibitors.
One of these proteases (Histidine Aspartic Protease, HAP) is homologous to three other aspartic proteases involved in hemoglobin metabolism but has a histidine in place of one of the two aspartic acids involved in catalysis.
 
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