protease

(redirected from Aspartic protease)
Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

endopeptidase

 [en″do-pep´tĭ-dās]
any peptidase that catalyzes the cleavage of internal bonds in a polypeptide or protein. Inhibition of the action of endopeptidases (proteases) in viruses causes formation of noninfectious particles; certain antiviral drugs work in this way (see protease inhibitors). Called also protease and proteinase.

pro·te·ase

(prō'tē-āz),
Descriptive term for proteolytic enzymes, both endopeptidases and exopeptidases; enzymes that hydrolyze (break) polypeptide chains.

protease

/pro·te·ase/ (pro´te-ās) endopeptidase.

protease

(prō′tē-ās′, -āz′)
n.
Any of various enzymes, including the endopeptidases and exopeptidases, that catalyze the hydrolytic breakdown of proteins. Also called peptidase.

protease

[prō′tē·ās]
an enzyme that is a catalyst in the breakdown of peptide bonds that join the amino acids in a protein. See also proteolysis.

pro·te·ase

(prō'tē-ās)
Descriptive term for proteolytic enzymes, both endopeptidases and exopeptidases; enzymes that hydrolyze (i.e., break) polypeptide chains.

protease

One of a range of protein-splitting enzymes. One focus of current interest in proteases is in their role in breaking down tissue barriers in the spread of cancer. High concentrations of the activator of one of these proteases has been found to be associated with a poor outlook in cancers of the colon and rectum.

protease

any enzyme that splits proteins, such as PEPSIN, TRYPSIN, EREPSIN or RENNIN.

protease

; proteinase enzyme that breaks down/proteolyses protein

protease

any proteolytic enzyme.

protease-antiprotease imbalance
thought to play a part in the pathogenesis of emphysema by permitting excessive proteolysis, especially of elastin.
fecal protease
originate from the pancreas and include trypsin, chymotrypsin and carboxypeptidases. Proteolytic activity of the feces may be evaluated by tests that measure digestion of gelatin or casein-based substrates.
α1-protease inhibitor
α1-antitrypsin.
References in periodicals archive ?
Cloning and characterization of an endo-[beta]-1,3(4)glucanase and an aspartic protease from Phaffia rhodozyma CBS 6938.
Starving the malaria parasite: inhibitors active against the aspartic proteases Plasmepsins I, II, and IV.
Cloning of cDNA for mosquito lysosomal aspartic protease.
Plant protease inhibitors effective against aspartic proteases from Coffee Berry Borer (Hypothenemus hampei)
An inhibitor from Lupinus bogotensis seeds effective againsts aspartic proteases from Hypothemus hampei.
The digestive fluid of the coffee berry borer, Hypothenemus hampei, larvae contains aspartic proteases, which show greatest activity at pH 3.
We believe the present paper to be not only the first report but also the first electrophoretic evidence by using zimograms of [alpha]AI proteolysis with endogenous aspartic proteases from H.
serine proteases) is considered a primitive character in Coleoptera and that cysteine, metallo-and aspartic proteases have arisen and selected through evolution, Cerambycidae has likely maintained or returned to an ancestral state by utilizing serine proteases, which may be considered as a feature of this taxonomic family (Johnson and Rabosky 2000; Crook et al.
PLASMEPSINS AND OTHER ASPARTIC PROTEASES AS DRUG TARGETS
Fungal aspartic proteases as possible therapeutic targets