In 2005, WHO established its Southeast Asian Influenza
Clinical Research Network to study neuraminidase inhibitor treatment of patients infected with viruses that possess pandemic potential (4).
During the Asian influenza
pandemic of 1957, studies suggested a possible increase in defects of the central nervous system (10-12) and several other adverse outcomes, including birth defects, spontaneous pregnancy loss, fetal death, and preterm delivery (8).
In the 20th century, 3 influenza-related pandemics occurred (1918 Spanish influenza, 1957 Asian influenza
, and 1968 Hong Kong influenza) (1), which are now known to represent 3 different antigenic subtypes of the influenza A virus: H1N1, H2N2, and H3N2.
Discussion after paper: the mechanism of spread of Asian influenza
D] chosen to yield an infected attack rate [approximately equal to] 50% to reflect the 1957-58 Asian influenza
In all human viruses (with the few exceptions of early isolates from the Asian influenza
outbreak ), Leu-226 is associated with Ser-228, while Gln-226 is associated with Gly-228 in avian viruses.
Following these researchers' experience with the emergence of penicillin-resistant staphylococci during the 1957-58 Asian influenza
pandemic, they commented ".