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a form of granulomatous inflammation characteristically observed in acute rheumatic carditis; fully developed Aschoff bodies consist of fibrinoid change in connective tissue, lymphocytes, occasional plasma cells, and abnormal characteristic histiocytes.
Synonym(s): Aschoff nodules
Etymology: Karl A.L. Aschoff, German pathologist, 1866-1942; AS, bodig
tiny rounded or spindle-shaped nodules containing multinucleated giant cells, fibroblasts, and basophilic cells. They are found in joints, tendons, the pleura, and the cardiovascular system of rheumatic fever patients.
Asch·off bod·ies(ahsh'of bod'ēz)
A form of granulomatous inflammation observed in acute rheumatic carditis.
Aschoff,Karl Ludwig, German pathologist, 1866-1942.
Aschoff bodies - a form of granulomatous inflammation characteristically observed in acute rheumatic carditis. Synonym(s): Aschoff nodules
Aschoff cell - a large-cell component of rheumatic nodules in the myocardium.
Aschoff nodules - Synonym(s): Aschoff bodies
node of Aschoff and Tawara - a small node of modified cardiac muscle that gives rise to the atrioventricular bundle of the conduction system of the heart. Synonym(s): atrioventricular node; Tawara node
Rokitansky-Aschoff sinuses - see under Rokitansky