ARSB

(redirected from Arylsulfatase B)
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ARSB

A gene on chromosome 5q11-q13 that encodes arylsulfatase B, which hydrolyses sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate and dermatan sulfate.

Molecular pathology
Defects in ARSB cause mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome).
References in periodicals archive ?
Naglazyme is a normal variant form of arylsulfatase B IUPAC name N-acetylgalactosamin 4-sulfatase) that is lacking in mucopolysaccharidosis VI patients.
Activities of arylsulfatase B and [beta]-galactosidase of 18.
In addition, BioMarin announced that it has completed patient enrollment of a Phase I clinical trial of rhASB, recombinant human arylsulfatase B, as enzyme replacement therapy for patients with MPS-VI.