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aryl hydrocarbon hydroxylase

   Also found in: Acronyms 0.01 sec.
aryl hydrocarbon hydroxylase (AHH),
an enzyme that converts carcinogenic chemicals in tobacco smoke and in polluted air into active carcinogens within the lungs. Aryl hydrocarbon hydroxylase is the subject of numerous studies to determine why cancer develops in some smokers but not in others. Experimental blood tests indicate that the level of aryl hydrocarbon hydroxylase may be a factor in hereditary predisposition of a cigarette smoker to cancer.


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Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol: evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.
33), newborns from smokers with high placental aryl hydrocarbon hydroxylase (AHH) activity (CYP1A1-related) had lower birth weights than newborns from smokers with lower placental AHH activity.
Characteristic enzymes of each phase, such as aryl hydrocarbon hydroxylase in phase I and glutathione-S-transferase in phase II, are encoded by genes that are highly variable.
 
 
 
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