silver nitrate

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Related to Argentum nitricum: Strophanthus gratus

silver

 [sil´ver]
a chemical element, atomic number 47, atomic weight 107.870, symbol Ag. (See Appendix 6.) It is used in medicine for its caustic, astringent, and antiseptic effects. It is also used in dentistry in alloys, in soldering, and as cones to obliterate the root canal.
silver nitrate colorless or white crystals, used as a caustic and local antiinfective; an important use is in prevention of ophthalmia neonatorum.
silver protein silver made colloidal by the presence of, or combination with, protein; an active germicide with a local irritant and astringent effect.
silver sulfadiazine the silver derivative of sulfadiazine, having bactericidal activity against many gram-positive and gram-negative organisms, as well as being effective against yeasts; used as a topical antiinfective for the prevention and treatment of wound sepsis in patients with second and third degree burns.
toughened silver nitrate a mixture of silver nitrate with hydrochloric acid, sodium chloride, or potassium nitrate, occurring as white crystalline masses molded into pencils or cones; a convenient means of applying silver nitrate locally.

sil·'ver ni·trate

an antiseptic and astringent; formerly used externally, in solution, in the prevention of ophthalmia neonatorum; also used in the special staining of the nervous system, spirochetes, reticular fibers, Golgi apparatus, nucleolar organizer region, and calcium.

silver nitrate

n.
A poisonous colorless crystalline compound, AgNO3, that becomes grayish black when exposed to light in the presence of organic matter and is used in manufacturing photographic film, silvering mirrors, dyeing hair, plating silver, and in medicine as a cautery and antiseptic.

silver nitrate (AgNO3)

a topical antiseptic.
indications A 1% solution was traditionally prescribed for the prevention of gonococcal ophthalmia in newborns, but povidone iodine is now usually used because it is less expensive and has a broader spectrum of action. Stronger concentrations can also be used on wet dressings for cauterizing wounds, removal of granulation tissue and warts, and prophylaxis following burns.
contraindication Known sensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are severe local inflammation, burns, and argyria, and staining.

silver nitrate

An astringent drug formerly used in solution to treat various conditions such as CONJUNCTIVITIS, OTITIS EXTERNA and cervical erosion. It causes black staining and is now seldom used in the Western world. The drug is on the WHO official list.
silver nitrate; AgNO3 topical agent causing brown staining and precipitation of a keratin-based eschar when applied to skin; antiseptic and astringent (i.e. <5% concentration); escharotic (i.e. >5% to < 20% concentration) and caustic (i.e. >25% concentration); action on skin mitigated by immersion in saline solution; used to treat mosaic verruca (see trichloroacetic acid) Table 1
Table 1: Caustic agents used in podiatric practice to achieve local tissue destruction
AgentActionSpecial precautionsContraindications
Monochloroacetic acid (crystals or saturated solution) e.g. single VPKeratolytic; hydrolysing agent
Non-self-limiting
Deep penetration
Painful
Do not use mask if applying solution
Use a mask if applying crystals
Review in 5-7 days
Neutralize with foot bath ± NaHCO3 or NaCl
Soft-tissue atrophy
Peripheral vascular disease
Sensory neuropathy
Salicylic acid paste (40-70%) e.g. single VP; plantar hard cornKeratolytic; hydrolysing agentMacerates tissues
Review in 7-14 days
May be used in conjunction with monochloroacetic acid crystals
Neutralize with foot bath ± NaHCO3 or NaCl
Soft-tissue atrophy
Peripheral vascular disease
Sensory neuropathy
Pyrogallic acid e.g. single VPKeratolytic; oxidizing agentDeep penetration
Review in 3-5 days
Prolonged caustic action
Do not apply more than 3 times sequentially
Stains skin black/brown
Use with great care: may cause deep tissue breakdown
Soft-tissue atrophy
Peripheral vascular disease
Sensory neuropathy
Trichloroacetic acid (saturated solution; 10% solution) e.g. mosaic VPMild keratolytic
Protein precipitant
Shallow penetration
Neutralize with foot bath ± NaHCO3 or NaCl
Review in 3 weeks
Peripheral vascular disease
Sensory neuropathy
Silver nitrate (70% solution; 75-95% stick) e.g. mosaic VP; as a protective skin application below a maskProtein precipitant
Self-limiting
Stains skin black/brown
Maximum effect occurs within 24 hours
Some patients show hypersensitivity to silver nitrate (or experience acute pain)
Neutralize with NaCl foot bath
May be applied in alternate layers with trichloroacetic acid
Peripheral vascular disease
Known sensitivity
Potassium hydroxide (KOH; 85% pellets)Strong keratolyticPotentially deep penetration
Action of KOH stopped by application of 5% acetic acid after macerated coagulum has been removed
Single treatment
Soft-tissue atrophy
Peripheral vascular disease
Sensory neuropathy
Phenol (80% solution or 100% crystal)Protein precipitateAction retarded by flooding with industrial methylated spirit
Skin overspill flooded with glycerine
Review as per postoperative protocol
Peripheral vascular disease (phenol suppresses inflammatory response)

VP, verruca pedis.

sil·ver ni·trate

(silvĕr nītrāt)
Antiseptic and astringent.

silver

1. a chemical element, atomic number 47, atomic weight 107.870, symbol Ag. See Table 6. It is used in medicine for its caustic, astringent and antiseptic effects. Experimental poisoning with silver salts causes myopathy.
2. a coat color in dogs, foxes.

silver amalgam
see amalgam.
silver collie syndrome
see canine cyclic hematopoiesis.
silver grass
aristidacontorta.
silver halide
any of the silver salts with halogens including bromine, chlorine, iodine used in photographic emulsion.
silver iodide
soluble silver salt used in cloud seeding but presents no toxicological risk to local grazing cattle.
silver-leaf ironbark
eucalyptusmelanophloia.
silver-leafed nightshade
solanumelaeagnifolium.
silver nitrate
colorless or white crystals, used as a caustic and local anti-infective.
silver nitrate (toughened)
a mixture of silver nitrate with hydrochloric acid, sodium chloride or potassium nitrate, occurring as white crystalline masses molded into pencils or cones, called caustic pencils; a convenient means of applying silver nitrate locally. Called also lunar caustic.
silver protein
silver made colloidal by the presence of, or combination with, protein; an active germicide with a local irritant and astringent effect.
silver stain
a method of demonstrating flagella on bacteria, or for visualizing very thin bacteria, such as leptospires.
silver sulfadiazine
the silver salt of sulfadiazine, having bactericidal activity against many gram-positive and gram-negative organisms, as well as being effective against yeasts; used as a topical anti-infective for the prevention and treatment of wound sepsis in patients with second and third degree burns.
silver weed
References in periodicals archive ?
Dr Tanvir Jamil recommends colocynth (bitter cucumber) 6C, and/or argentum nitricum (silver nitrate) 6C, four times daily.
Argentum Nitricum - Conjunctiva scarlet, swollen eyes, better with cold.
Sally's symptoms matched the picture of Argentum nitricum (silver nitrate).