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Argentine hemorrhagic fever |
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Argentine hemorrhagic fever, an acute febrile viral illness caused by an arenavirus transmitted to humans by contact with or inhalation of aerosolized excreta of infected rodents. Initially, it is characterized by chills, fever, headache, myalgia, anorexia, nausea, vomiting, and a general feeling of malaise. As the disease progresses, the victim may develop a high fever, dehydration, hypotension, flushed skin, abnormally slow heartbeat, bleeding from the gums and internal tissues, hematuria, and hematemesis. There may be involvement of the central nervous system, shock, and pulmonary edema. There is no specific treatment for the disease other than hydration, rest, warmth, and adequate nutrition. Rarely, IV fluids and dialysis are necessary. Usually, the prognosis is complete recovery. See also Arenavirus, Bolivian hemorrhagic fever, Lassa fever. Argentine hemorrhagic fever A viral illness caused by the Junin arenavirus Epidemiology Transmitted by contact with rodent urine; 23 outbreaks have been recorded, in the maize-producing region of Argentina Rodent vectors Akodon arenicola,
Calomys laucha, C musculinus Clinical 1-2 wk incubation, followed by mucocutaneous hemorrhage, fever, anorexia, N&V, fluid loss and oliguria, hypotension, shock, severe myalgia, leukopenia, thrombocytopenia, transient hypocomplementemia
Management Rehydration; high–15-45% mortality may ↓ to 1-4% with convalescent serum-
specific Junin virus immune plasma How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Importance of dose of neutralising antibodies in treatment of Argentine haemorrhagic fever with immune plasma. Efficacy of immune plasma in treatment of Argentine haemorrhagic fever and association between treatment and a late neurological syndrome. |
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