arachidonic acid

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arachidonic acid

 [ah-rak″ĭ-don´ik]
an essential fatty acid that cannot be synthesized by animal tissues and must be obtained in the diet.

ar·a·chi·don·ic ac·id

(ă-rak-i-don'ik as'id),
An unsaturated fatty acid, usually essential in nutrition; the biologic precursor of the prostaglandins, the thromboxanes, and the leukotrienes (collectively known as eicosanoids).

arachidonic acid

/arach·i·don·ic acid/ (ah-rak″ĭ-don´ik) a polyunsaturated 20-carbon essential fatty acid occurring in animal fats and formed by biosynthesis from linoleic acid; it is a precursor to leukotrienes, prostaglandins, and thromboxane.

arachidonic acid

(ăr′ə-kĭ-dŏn′ĭk)
n.
An unsaturated fatty acid, C20H32O2, present in animal fats and synthesized by the body from linoleic acid, that is essential in human nutrition and is a precursor in the biosynthesis of some prostaglandins.

arachidonic acid

[ar′əkidon′ik]
Etymology: L, arachos, a legume
a long-chain polyunsaturated fatty acid that is a component of lecithin and serves as a starting material in the biosynthesis of prostaglandins and leukotrienes. In mammals, arachidonic acid is synthesized from linoleic acid.

arachidonic acid

Biochemistry
A polyunsaturated omega-6 fatty acid, which is an essential dietary component for mammals and the precursor for biosynthesis of prostaglandins, thromboxanes and hydroxy-eicosatetraenoic acid derivatives (e.g., leukotrienes). Arachidonic acid release from phospholipids is the limiting step in forming its active metabolites.

Nutrition
Foods containing arachidonic acid—e.g., egg yolks, fatty red meat and organ meats—are viewed as unhealthy by nutritionists.

ar·a·chi·don·ic ac·id

(ar'ă-ki-don'ik as'id)
Liquid unsaturated fatty acid that occurs in most animal fats; considered essential in animal nutrition.

arachidonic acid

An unsaturated fatty acid, formed from LINOLENIC acid, and a precursor of prostaglandins and thomboxanes.

arachidonic acid

cell membrane constituent which undergoes degradation during inflammation to form prostaglandins and cytokines, with resultant increase in the inflammatory response; arachidonic acid breakdown is disrupted by non-steroidal anti-inflammatory drugs, aspirin and steroids (see aspirin; non-steroidal anti-inflammatory drugs; steroids)

ar·a·chi·don·ic ac·id

(ar'ă-ki-don'ik as'id)
An unsaturated fatty acid, usually essential in nutrition; the biologic precursor of the prostaglandins, the thromboxanes, and the leukotrienes (collectively known as eicosanoids).

arachidonic acid (ar´əkədon´ik),

n an essential fatty acid that is a com-ponent of lecithin and a basic material for the biosynthesis of some prostaglandins.
Arachnia propionica,
n an opportunistic, naturally occurring organism in the body, especially in body cavities and on the skin. It is sometimes implicated in actinomycosis, especially in open wounds.

arachidonic acid

twenty carbon fatty acid containing four double bonds of the n-6 family essential fatty acids from which prostaglandins, thromboxane and leukotrienes are derived. Deficiency, which is characterized by hair loss, fatty liver degeneration, anemia and reduced fertility, occurs most commonly in cats because of their inability to synthesize arachidonic acid from linoleic acid.
References in periodicals archive ?
2] activation, manifested by a drop in arachidonic acid release, was accompanied by a marked reduction in apoptosis and PAF generation, and a decline in PG[E.
Rather, the level of arachidonic acid is lower in the elderly male than the young female.
None of the specimens contained arachidonic acid ethyl ester, which is the most susceptible to light and heat of those in the profile.
The team found that in that experimental system, one variant makes prostaglandins from arachidonic acid.
We may be able to deter starfish from devouring coral reefs by finding a way to release cheap a-linolenic acid that has the same effect as arachidonic acid,'' Uemura said.
2[Alpha]] production depends on the hydrolysis of esterified arachidonic acid (from membrane phospholipid) which yields unesterified arachidonic acid.
The text mainly focuses on the production of the long chain polyunsaturated fatty acids, Arachidonic acid, and Docosahexaenoinc acid.
15, 2014 /PRNewswire/ -- Research and Markets has announced the addition of the "Global and Chinese Arachidonic Acid (ARA) Industry Report 2014 " report to their offering.
Eicosapentaenoic acid (EPA), an omega-3 fatty acid, has an anti-inflammatory effect, which results from the fact that it is an alternative substrate to arachidonic acid (an omega-6 fatty acid) in prostaglandin and leukotriene biosynthesis.
We have investigated in vitro the effects of treatment with either pomegranate juice (PJ) or the polyphenol-rich extract from pomegranate fruit (POMx) on platelet aggregation, calcium mobilization, thromboxane A(2) production, and hydrogen peroxide formation, induced by collagen and arachidonic acid.
They discuss their prevalence, pathophysiology, and existing therapeutic options; what constitutes a lipid and how it is broken down to generate biologically active mediators; mediators like arachidonic acid, platelet-activating factor, and lysophosphatidic acid, how they act, and their role in airway inflammation; the products of arachidonic acid metabolism, such as leukotrienes, prostaglandins, epieicosatrienoic acid, and oxoeicosatetraenoic acid; anti-inflammatory lipid mediators such as lipoxin and drug discovery efforts to mimic lipoxin action; enzymes that affect the process of lipid mediator synthesis, their biology, and drug discovery efforts; the role of sphingosine and ceramide; and kinases.