aptamer

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aptamer

A short biomolecule (e.g., an oligonucleotide or peptide) that binds to a specific target molecule—e.g., dopamine, HIV TAR, hemin, IFN-gamma, lysozyme, thrombin and vascular endothelial growth factor (VEGF). Decoy aptamers inactivate DNA-binding proteins (e.g., transcription factors), thereby activating or inactivating genes.

aptamer

(ap′tă-mĕr) [L. aptus, fitted, appropriate + -mere]
A chemical, usually a protein or a nucleic acid, that can fashion itself into numerous shapes, e.g., the configuration of a cell surface receptor.
References in periodicals archive ?
Besides a discussion on the properties of aptamers in the technological analysis, the basics on nucleic acid aptamers, peptide aptamers and the SELEX method for their synthesis are also discussed.
As well as a discussion on the properties of aptamers in the technological analysis, the basics on nucleic acid aptamers, peptide aptamers and the SELEX method for their synthesis are also discussed.