apramycin


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apramycin

an aminoglycoside antibiotic, active against gram-negative and gram-positive bacteria. It is water soluble, easily administered in drinking water and has been used largely in treating intestinal infections in pigs and calves.
References in periodicals archive ?
Apramycin resistance plasmids in Escherichia coli: possible transfer to Salmonella typhimurium in calves.
High frequency transfer and horizontal spread of apramycin resistance in calf faecal Escherichia coli.
Gentamicin and apramycin were also clustered together, with a more than 50 percent degree of similarity (Cluster 2) (Figure 1).
Isolates exhibiting apramycin resistance were observed and a representative isolate was taken for further study.
Figure 1 shows that the bacteria from chickens 5 and 6 were resistant to apramycin while the rest were sensitive.
The lack of resistance also indicates that the AME causing amikacin resistances is not formed in response to apramycin exposure.
Gentamicin resistance only occurred where apramycin resistance occurred (Comparing Figures 1 and 3).
The lack of resistance also indicates that the AME causing kanamicin resistance is not formed in response to apramycin exposure.
Streptomycin is not used by PIANZ and it is not believed to be a substrate of the AME caused by exposure to apramycin.
Nucleic acid hybridization with a probe specific for 3-aminoglycoside acetyltransferase type IV: a survey of resistance to apramycin and gentamicin in animal strains of Escherichia coli.
High genetic homology between plasmids of human and animal origins conferring resistance to the aminoglycosides gentamicin and apramycin.