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amyloid precursor protein
amyloid precursor protein (APP)
a large transmembrane glycoprotein expressed on the cell surface and of uncertain function; it may be cleaved on the cell surface to a soluble form. Alternatively, cleavage may follow endocytosis and in some cases then yields 40 to 43 abnormal amino acid peptides, which aggregate to form Ab amyloid, associated with Alzheimer's disease.
APP A gene on chromosome 21q21.3 that encodes a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form various peptides.
APP mutations are implicated in autosomal dominant Alzheimer’s disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
APP Amyloid β protein precursor A membrane-spanning glycoprotein of unknown function, which is expressed in many mammalian tissues, the gene for which maps to chromosome 21. See Alzheimer's disease, β-amyloid.
References in periodicals archive
Live is free mobile app builder software that allows a person/individual to create a highly customized smartphone app with no experience necessary and no coding knowledge; the only requirement for creating an app is to sign up for free and input their information.
, a develop of social media marketing applications, announced today that its platform has been integrated with Facebook Places to allow businesses a way to interact with customers based on their off-line activities.
Companies want to see their social media investment drive sales," said Jon Siegal, Founder & CEO, Fan Appz
com)-- Rad Appz
is pleased to announce their first Android app that is designed for anyone keen to discover the joys of camping.