In 1 fatal case, the invasive zygomycete Apophysomyces
elegans was isolated.
Similarly, a cluster of mucormycosis cases caused by Apophysomyces
trapeziformis occurred among 13 persons who were severely injured in the May 22, 2011, tornado in Joplin, Missouri, United States (4).
The Joplin cases were caused by the fungus Apophysomyces
trapeziformis, which is commonly found in soils, decaying vegetation, and water containing organic matter such as leaves and soil.
Laboratory analysis for all 13 patients yielded the Mu-cormycete Apophysomyces
Other fungi occasionally isolated include Mycocladus (Absidia) corymbifera, Rhizomucor pusillus, Apophysomyces
elegans, Saksenaea vasiformis, Mucor species, and Cunninghamella bertholletiae.
The rest of the patients were infected with the following organisms: Aspergillus species (four cases), Pseudallescheria boydii (two cases), Coccidioides immitis (one case), Histoplasma capsulatum (one case), Ramichloridium mackenziei (one case), and Apophysomyces
elegans plus a Basidiomycetes species (one case).
1) The zygomycetes include Rhizopus, Absidia, Cunninghamella, Rhizomucor, Synchephalastrum, Saksenaea, Apophysomyces
, and Mucor.
The genera reported to cause invasive infection are Absidia, Mucor, Rhizomucor, Rhizopus, Apophysomyces
, Saksenaea, Cunninghamella, Cokeromyces and Syncephalastrum.
Zygomyeosis due to Apophysomyces
elegans: Report of 2 cases and review of the literature.
The most common agents in human infection comprise the genera Rhizopus, Mucor, Absidia, Apophysomyces
, Cunninghamella, Rhizomucor, and Saksenaea.
To the Editor: The fungus Apophysomyces
elegans (order Mucorales) is a thermotolerant species that causes severe infections among humans.
Rhino-orbitocerebral mucormycosis caused by Apophysomyces