apomorphine

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apomorphine

(ăp′ə-môr′fēn′)
n.
A poisonous alkaloid, C17H17NO2, that is an analog of morphine and is used medicinally to treat Parkinson's disease and to induce vomiting.

apomorphine

an antiparkinson agent.
indications This drug is used for acute, intermittent treatment of hypomobility episodes in advanced parkinsonism.
contraindications Known hypersensitivity to this drug prohibits its use.
adverse effects Adverse effects of this drug include psychosis, hallucination, depression, dizziness, headache, confusion, yawning, dyskinesias, drowsiness, somnolence, edema, syncope, tachycardia, blurred vision, rhinorrhea, sweating, vomiting, constipation, dysphagia, dry mouth, impotence, and urinary frequency. Life-threatening side effects include sleep attacks, hemolytic anemia, leukopenia, and agranulocytosis. Common side effects include agitation, orthostatic hypotension, nausea, and anorexia.

apomorphine

A morphine derivative used as an expectorant, emetic, and hypnotic. In large doses it promotes severe vomiting. Used in the treatment of Parkinson's disease. Brand names are Apo-go and Uprima.

apomorphine

an alkaloid from morphine. Used as the hydrochloride; administered parenterally it causes vomiting within 3 to 10 minutes but can also be administered orally. Stimulates receptors in the chemoreceptor trigger zone of the medulla oblongata.