isosorbide dinitrate

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i·so·sor·bide di·ni·trate

(ī'sō-sōr'bīd dī-nī'trāt),
A coronary vasodilator that acts via the formation of nitric oxide.

isosorbide dinitrate

(ī′sō-sôr′bīd′ dī-nī′trāt′)
n.
A vasodilator drug, C6H8N2O8, used to treat and prevent angina pectoris.

isosorbide dinitrate

[-sôr′bīd]
an antianginal agent. Its prototype is nitrogycerin.
indications It is prescribed as a coronary vasodilator in the treatment of angina pectoris and congestive heart failure and esophageal spasm caused by GI reflux.
contraindications Closed-angle glaucoma, known hypersensitivity to this drug, concurrent use of drugs for erectile dysfunction, narrow-angle glaucoma, head trauma, or severe anemia prohibits its use.
adverse effects The most serious effect is occasional marked hypotension. Flushing, headache, lightheadedness, and dizziness may also occur.

isosorbide dinitrate

Cardiology A venodilating nitrate used with hydralazine in CHF; ID ↓ cardiac filling pressure, ↑ exercise tolerance. See Nitrates.

isosorbide dinitrate

A drug used to prevent or relieve ANGINA PECTORIS and in to treat HEART FAILURE. The drug is on the WHO official list. Brand names are Angitak, Cedocard Retard, Isoket and Isotek Retard.

isosorbide dinitrate (ī´sōsor´bīd dīnī´trāt),

n brand names: Iso-Bid, Isotrate, Dilatrate-SR, Isordil;
drug class: nitrate antianginal; action: decreases preload/afterload, which is responsible for decreasing left ventricular end-diastolic pressure, systemic vascular resistance;
uses: chronic stable angina pectoris, prophylaxis of angina pain.