allopurinol

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Related to Apo-Allopurinol: Zyloprim

allopurinol

 [al″o-pūr´ĭ-nol]
a drug that inhibits uric acid production and reduces serum and urinary uric acid levels; used for treatment of hyperuricemia of gout and prophylaxis and treatment of hyperuricemia secondary to blood dyscrasias or cancer chemotherapy and of uric acid nephropathy, as well as for prophylaxis of kidney stone formation.

al·lo·pu·ri·nol

(al'ō-pū'ri-nol),
Inhibitor of xanthine oxidase to inhibit uric acid formation; used in the treatment of gout and to retard the rapid metabolic degradation of 6-mercaptopurine.

allopurinol

/al·lo·pur·i·nol/ (al″o-pūr´ĭ-nol) an isomer of hypoxanthine, capable of inhibiting xanthine oxidase and thus of reducing serum and urinary levels of uric acid; used in prophylaxis and treatment of hyperuricemia and uric acid nephropathy and prophylaxis of renal calculus recurrence.

allopurinol

(ăl′ō-pyo͝or′ə-nôl′, -nōl′, -nŏl′)
n.
A drug, C5H4N4O, that inhibits uric acid formation in the body and is used to treat conditions, especially gout, that cause elevated uric acid levels.

allopurinol

[al′əpyo̅o̅r′ənôl]
a xanthine oxidase inhibitor uricosuric agent.
indications It is prescribed in the treatment of gout and other hyperuricemic conditions.
contraindications It is not prescribed for children (except those with hyperuricemia resulting from malignancy), lactating mothers, or people suffering an acute attack of gout. Known hypersensitivity to this drug prohibits its use.
adverse effects Among the most serious adverse reactions are blood dyscrasias and severe rashes and other allergic reactions. GI and ophthalmological disturbances also may occur.

allopurinol

A xanthine oxidase inhibitor which lowers high uric acid and thus is effective for both primary (e.g., gout) and secondary­ (e.g., due to hematologic disorders or neoplasa) hyperuricemia.
 
Pharmacology
Allopurinol and its primary metabolite, oxypurinol, inhibit xanthine oxidase; oral absorption; peak plasma at < 1 hour; T1⁄2 2–3 hours.
 
Adverse effects
Hypersensitivity reaction.

allopurinol

Zyloprim® Therapeutics A xanthine oxidase inhibitor which lowers high uric acid and thus is effective for both 1º–eg gout and 2º–eg due to hematologic disorders or neoplasa–hyperuricemia Pharmacology Allopurinol and its 1º metabolite, oxypurinol, inhibit xanthine oxidase; oral absorption; peak plasma at < 1 hr; T1⁄2 2-3 hrs Adverse effects Hypersensitivity reaction

allopurinol

A drug used to treat gout. Allopurinol is a xanthine oxidase inhibitor which reduces the production of uric acid from nucleic acid breakdown. The drug is on the WHO official list. A brand name is Zyloric.

Allopurinol

A drug that corrects hyperuricemia by inhibiting urate production.
Mentioned in: Gout

allopurinol

drug used for long-term treatment of gout, in a daily dose proportional to disease severity (mild presentation: 100-200 mg; moderate to severe presentation: 300-600 mg; severe presentation: 700-900 mg); it is not indicated for asymptomatic hyperuricaemia

al·lo·pu·ri·nol

(al'ō-pū'ri-nol)
Inhibitor of xanthine oxidase to inhibit uric acid formation; used treat gout and retard rapid metabolic degradation of 6-mercaptopurine.

allopurinol (al´əpyōō´rinol),

n brand names: Lopurin, Zyloprim;
drug class: antigout drug;
action: inhibits the enzyme xanthine oxidase, reducing uric acid synthesis;
uses: chronic gout, hyperuricemia associated with malignancies.

allopurinol

a drug that inhibits uric acid production and reduces serum and urinary uric acid levels; used in the treatment of urate uroliths in dogs.