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apolipoprotein E
(redirected from Apo E)

   Also found in: Wikipedia 0.01 sec.
apolipoprotein E,
a protein component of lipoprotein complexes found in very-low-density lipoprotein (VLDL), high-density lipoprotein, chylomicrons, and chylomicron remnants. It facilitates hepatic uptake of chylomicron and VLDL remnants and is elevated in patients with type III hyperlipoproteinemia. One form of apolipoprotein E has been linked to Alzheimer's disease.

apolipoprotein E
A 34-kD cholesterol-binding glycoprotein, which comprises 15% of VLDL; apoE maps to chromosome 19, is secreted by macrophages that mediate the uptake of lipoproteins–VLDL, HDL, LDL and cholesterol esters into cells via distinct binding domains for each receptor; apo-E has a central role in the metabolism of TG-rich lipoproteins, and mediates the uptake of chylomicrons and VLDL by the liver


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Each Apo E genotype combination differs in its ability to clear toxic substances from the body.
The APO E Gene Diet Pamela McDonald, FA, WHCNP, PNP, FNP Elite Books c/o Russel Public Communications 7290 E.
It's possible that identifying and treating this disorder in apo E [epsilon]4-positive patients could delay or perhaps even prevent the onset of cognitive decline and Alzheimer's dementia, according to Dr.
 
 
 
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