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apical membrane

   Also found in: Wikipedia 0.01 sec.
apical membrane,
the layer of plasma membrane on the apical side (the side toward the lumen) of the epithelial cells in a body tube or cavity, separated from the basolateral membrane by the zonula occludens.


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Despite an obvious cholesterol elevation, most excretory kidney functions, including organic anion excretion rate, are not influenced by the free cholesterol accumulation in proximal tubule cells, whereas some reabsorptive functions such as protein endocytosis and glucose reabsorption by the apical membrane appear to be vulnerable.
The nephrotoxicity risk in rats subjected to heavy muscle activity by Oner, Gulsen; Cirrik, Selma / Journal of Sports Science and Medicine
Fifteen cases of normal bladder epithelium (n = 15) demonstrated weak immunoreactivity for CD24 with well-confined localization in the apical cytoplasm or apical membranes (Figure 1, A through G, and Table 1).
Overexpression of CD24: association with invasiveness in urothelial ... by Choi, Yoon-La; Lee, Seung-Hyun; Kwon, Ghee-Young; Park, Cheol-Keun; Han, Jae-Joon; Choi, Jong Sun; C / Archives of Pathology & Laboratory Medicine
In the thyroid gland, a disorder in the function of pendrin may cause diminished iodide transport over the apical membrane that results in iodide remaining in the thyrocyte and a consequent decrease of organification of iodide.
Genetic factors that might lead to different responses in individuals ... by Fowler, Bruce A. / Environmental Health Perspectives
 
 
 
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