primary progressive aphasia

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primary progressive aphasia

a speech disorder seen with certain degenerative brain diseases, consisting of deterioration of speech and language ability over a period of years without significant loss of memory or ability to understand language.

primary progressive aphasia

A subtype of frontotemporal lobar degeneration characterised by reduced speech production, speech errors, and word retrieval difficulties resulting in mutism and an inability to communicate; memory is relatively preserved, at least in the early stages of disease.

pri·mar·y pro·gres·sive a·pha·si·a

(PPA) (prī'mar-ē prŏ-gres'iv ă-fāz'ē-ă)
A degenerative disorder of which the early major symptom is an aphasia that increases in severity and (usually) eventually includes dementia.

primary progressive aphasia

An atypical form of DEMENTIA featuring progressive loss of the language function without severe memory loss, loss of visual and spacial skills or deterioration in behaviour. The defect is essentially one of word comprehension so that there is inexorable loss of the ability to find an appropriate word or name objects (anomia) or to employ normal syntax. The condition is associated with focal degeneration in the speech areas on the left temporal lobe of the brain, but it is not considered to be a subset of Alzheimer's disease.