Also found in: Dictionary, Thesaurus.
buspironeAn anti-anxiolytic psychotropic agent of the azaspirodecanedione class, which is unrelated to benzodiazepines, barbiturates or other sedatives.
Dizziness, insomnia, nervousness, drowsiness, lightheadedness, nausea, diarrhoea, headache, fatigue.
Avoid MAOIs when using buspirone.
Oral and transdermal; initial adult dosage is 15 mg/day; maximum, 60 mg/day.
Mechanism of action
Buspirone has an affinity for both serotonin (5-HT1A) and dopamine (D2) receptors; its mechanism of action is currently unknown.