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antitoxin

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antitoxin /an·ti·tox·in/ (an´te-) (an´ti-tok″sin) antibody produced in response to a toxin of bacterial (usually an exotoxin), animal (zootoxin), or plant (phytotoxin) origin, which neutralizes the effects of the toxin.an´titoxic
botulism antitoxin  an equine antitoxin against toxins of the types A and B and/or E strains of Clostridium botulinum.
diphtheria antitoxin  equine antitoxin from horses immunized against diphtheria toxin or the toxoid.
equine antitoxin  an antitoxin derived from the blood of healthy horses immunized against a specific bacterial toxin.
tetanus antitoxin  equine antitoxin from horses that have been immunized against tetanus toxin or toxoid.

an·ti·tox·in (nt-tksn)
n.
1. An antibody formed in response to and capable of neutralizing a specific biological toxin.
2. Serum containing antitoxins that is used to prevent or treat diseases caused by biological toxins, such as tetanus and diphtheria.

Antitoxin
An antibody that is capable of neutralizing the specific toxin (a specific cause of disease) that stimulated its production in the body and is produced in animals for medical purposes by injection of a toxin or toxoid with the resulting serum being used to counteract the toxin in other individuals.

antitoxin
[-tok′sin]
Etymology: Gk, anti + toxikon, poison
a subgroup of antisera usually prepared from the serum of horses immunized against a particular toxin-producing organism, such as botulism antitoxin given therapeutically in botulism and tetanus and diphtheria antitoxins given prophylactically to prevent those infections.

antitoxin [an´tĭ-tok″sin]
a particular kind of antibody produced in the body in response to the presence of a toxin; see also immunity. adj., adj an´titoxic.
botulism antitoxin an equine antitoxin against the toxins produced by the types A and B and/ or E strains of Clostridium botulinum; administered intravenously in the postexposure prophylaxis and treatment of botulism, other than infant botulism. Generally trivalent (ABE) antitoxin is used.
diphtheria antitoxin equine antitoxin from horses immunized against diphtheria toxin or the toxoid; administered intramuscularly or intravenously in the treatment of suspected cases of diphtheria.
equine antitoxin an antitoxin derived from the blood of healthy horses immunized against a specific bacterial toxin.
tetanus antitoxin equine antitoxin from horses that have been immunized against tetanus toxin or toxoid; used for the passive prevention and treatment of tetanus. It is rarely used, tetanus immune globulin being preferred.

antitoxin,
n a substance used to counter directly the effects of a toxin. May be produced by the body or administered from outside the body.

antitoxin (an´tētok´sin),
n a subgroup of antisera usually prepared from the serum of horses immunized against a particular toxin-producing organism, such as botulism antitoxin and diphtheria antitoxin given prophylactically to prevent those infections.

antitoxin
a particular kind of antibody produced in the body in response to the presence of a toxin or toxoid. Most commonly used in the treatment of diseases caused by clostridial toxins, e.g. botulinum and tetanus. See also immunity.

gas gangrene antitoxin
serum containing antitoxic antibodies; prepared from the blood of healthy animals immunized against gas-producing organisms of the genus Clostridium.
tetanus antitoxin
preparation from the blood serum or plasma of healthy animals immunized against tetanus toxin. Used for prophylaxis after injury because of its immediate effect. Active immunization is preferred for long-term protection, particularly for many clostridial diseases such as tetanus.

antitoxin
Immunology An antibody-rich serum from an animal stimulated with specific antigens or bacterial toxins–eg, botulinus, tetanus or diphtheria, which is used to provide passive immunity. See Passive immunity.


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Aside from administering diphtheria antitoxin, physicians could do very little for their patients except to recommend bed rest and a healthy diet.
Nevertheless, paralysis progressed after antitoxin administration; within 48 hours, the patient was quadriplegic with no voluntary muscle function or distal tendon reflexes.
The botulinum toxin is used at the Cummings School to develop antitoxin treatments under a food and waterborne diseases contract with the National Institutes of Health.
 
 
 
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