Antithrombin (redirected from Antithrombin III)

antithrombin /an·ti·throm·bin/ (-throm´bin) any naturally occurring or therapeutically administered substance that neutralizes the action of thrombin and thus limits or restricts blood coagulation.

---

antithrombin I  fibrin, referring to its capacity to adsorb thrombin and thus neutralize it.

antithrombin III  a plasma a of the serpin family that inactivates thrombin and also inhibits certain coagulation factors and kallikrein. Inherited deficiency is associated with recurrent deep vein thrombosis and pulmonary emboli; the complications are prevented and treated with a preparation of antithrombin III from pooled human plasma.

---

an·ti·throm·bin (nt-thrmbn, nt-)

n.

An anticoagulant that inhibits or prevents the effects of thrombin.

---

Antithrombin

Any substance that counters the effect of thrombin, an enzyme that converts fibrinogen into fibrin, leading to blood coagulation.

Mentioned in: Hypercoagulation Disorders

---

antithrombin

any naturally occurring or therapeutically administered substance that neutralizes the action of thrombin and thus limits or restricts blood coagulation.

---

antithrombin III (AT III)

an alpha₂-globulin synthesized in the liver which is a natural inhibitor of clotting.