antipruritic

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antipruritic

 [an″te-, an″ti-proo-rit´ik]
1. preventing or relieving itching.
2. an agent that so acts.

an·ti·pru·rit·ic

(an'tē-prū-rit'ik),
1. Preventing or relieving itching.
2. An agent that relieves itching.

antipruritic

/an·ti·pru·rit·ic/ (-proo-rit´ik) preventing or relieving itching, or an agent that does this.

antipruritic

(ăn′tē-pro͝o-rĭt′ĭk, ăn′tī-)
adj.
Preventing or relieving itching.
n.
An antipruritic drug.

antipruritic

[-proo͡rit′ik]
Etymology: Gk, anti + L, prurire, to itch
1 pertaining to a substance or procedure that tends to relieve or prevent itching.
2 an antipruritic drug. Topical anesthetics, corticosteroids, and antihistamines are used as antipruritic agents.

antipruritic

adjective Relieving or preventing itching.
 
noun An agent that prevents or relieves itching.

antipruritic

adjective Relieving or preventing itching noun An agent that prevents or relieves itching

an·ti·pru·rit·ic

(an'tē-prūr-it'ik)
1. Preventing or relieving itching.
2. An agent that relieves itching.

antipruritic

Any drug or other treatment effective in relieving itching.

antipruritic

topical agent preventing or relieving itching, i.e. decreasing sensitivity of local nerve endings (e.g. benzocaine), reducing local oedema (e.g. weak iodine solution; menthol; methyl salicylate), cooling skin (e.g. calamine lotion; kaolin powder; hamamelis water; cooling lotions; evaporating lotions) and counteracting histamine release (e.g. antihistamine cream, crotamiton creams [Eurax]) (Table 1 and see Table 2)
Table 1: Topical antipruritic and analgesic agents
AgentAction and usage
Benzocaine; 20% ointmentTreatment of painful heloma neurovasculare
Antipruritic in treatment of chilling
Menthol 2%Dusting powder
Menthol 10%In methyl salicylate ointment; used to reduce inflammation, e.g. hyperaemic phase of chilblains
KaolinDusting powder
Tetracaine 4% gel Ametop gel; Amethocaine 2% creamantipruritic and analgesic
Crotamiton 10% creamEurax: powerful and rapid antipruritic
Mepyramine maleate 2% creamAnthisan: rapidly antipruritic, for insect bites
Table 2: Topical dusting powders for use on skin
Base agents
Starch, Chalk, Magnesium carbonate, Kaolin, Talc, Zinc oxide, Zinc stearate The base agent should augment the action of the active ingredient
Active ingredients
ExamplesActionIndicated use
Boric acid 5%
Salicylic acid 3-10%
Alum 10%
Benzocaine 10%
Calamine
Chlorphensin 1%
Menthol 2%
Phenol 2.5%
Sodium perborate 15%
Sodium poly-metaphosphate 5%
Benzoin 10%
Undecenoic acid 2%
Zinc undecenoate 10%
Active against foetid bacteria
Astringent, antiseptic, antifungal
Strongly astringent and deodorant
Analgesic and antipruritic
Soothing, absorbent
Fungicidal
Fungicidal
Antipruritic and fungicidal
Antiseptic
Astringent
Astringent
Fungicidal
Fungicidal
Bromidrosis
Hyperhidrosis and mild fungal skin infection
Hyperhidrosis and bromidrosis
Irritant skin conditions
Irritant skin conditions
Fungal infections
Fungal infections
Irritant fungal infections
Mild skin infection
Prophylaxis of fungal infection
Hyperhidrosis
Fungal infection
Fungal infection

an·ti·pru·rit·ic

(an'tē-prūr-it'ik)
1. Preventing or relieving itching.
2. An agent that relieves itching.

antipruritic (an´tīprōōrit´ik),

adj relieving or preventing itching.

antipruritic

1. preventing or relieving itching.
2. an agent that counteracts itching; of special importance in the treatment of animals because of the self-trauma that results from their responses to pruritus.
References in periodicals archive ?
4,13) Corticosteroids and calcipotriol possess anti-inflammatory and antipruritic properties, likely explaining their efficacy in treating PN.
14) Their antipruritic effect, likely related to their influence on cutaneous sensory nerve fibers and inhibition of inflammatory cytokines, could also explain their efficacy in treating PN.
Whereas antihistamines exert their antipruritic effect by blocking histamine Hlreceptors, montelukast decreases pruritic symptoms by antagonizing leukotriene receptors.
Accordingly, oral naltrexone can be used to treat PN, as shown in an open-label clinical trial in which 9 out of 17 patients (53%) achieved high antipruritic effect, defined as a reduction of pruritic symptoms by at least half.
Most patients should notice some level of antipruritic efficacy and varying degrees of lesion flattening, softening, or healing.
For patients who have prurigo nodularis, thalidomide may be particularly effective as an antipruritic.
Remark Pharma BV is present in the largest dermatologicals categories with flagship brands such as Dr Swaab in nappy (diaper) rash treatments, antipruritics and topical germicidals/antiseptics, Resdan in medicated shampoos and Nestosyl in antipruritics.
Topical antifungals, hair loss treatments, medicated shampoos, antipruritics and haemorrhoid treatments have benefited most from the ageing population.
Johnson & Johnson maintains its leading position, holding a 16% retail value share through its diverse portfolio of leading brands in several dermatological sub-categories: Neutrogena T/Gel in medicated shampoos, Rogaine in hair loss treatments, Desitin in nappy (diaper) rash treatments, Aveeno in antipruritics, Tucks in haemorrhoid treatments, Benadryl in topical allergy remedies/antihistamines and Neosporin in topical germicidals/antiseptics.
Product coverage: acne treatments, antipruritics, topical germicidals/antiseptics, topical allergy remedies/antihistamines, topical antifungals, vaginal antifungals, antiparasitics/lice (head and body) treatments, medicated shampoos, hair loss treatments, lip care treatments, haemorrhoid treatments, child-specific medicated skin care, nappy (diaper) rash treatments
Omega Pharma's brands Canoderm and Miniderm in antipruritics led sales in 2014 with, respectively, 12% and 9% value shares each in retail value sales terms.
Other dermatologicals which consists of antiparasitics/lice (head and body) treatments, antipruritics, cold sore treatments, haemorrhoid treatments, topical allergy remedies and topical germicidals/antiseptics, all witnessed positive value growth in 2014.