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anticardiolipin antibody |
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anticardiolipin antibody Clinical immunology Any of a family of antibodies that recognize an epitope on the cardiolipin molecule; ACA are associated with immune-mediated disease, strokes, fetal wastage, syphilis, but are also found in healthy
subjects without disease, represent natural antibodies, and indicate a normally functioning immune system Normal values IgA < 22 APL–IgA Phospholipid Units–PLU; IgG < 22 GPL–IgG PLUs; IgM < 11 MPL–IgM PLUs. Cf
Antiphospholipid syndrome. Patient discussion about Antiphospholipid syndrome. Q. what is anh cardiolipin antibody A. Cardiolipin is a protein that is very common in the body. Mostly on heart and skeletal muscles. During several illnesses, mostly autoimmune, our body creates an antibody against it that do great damage and needs to cbe controlled. Read more or ask a question about Antiphospholipid syndromeHow to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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NB: Antiphospholipid syndrome - the presence of antiphospholipid antibodies (cardiolipin and/or lupus anticoagulant) is strongly associated with a history of multiple thromboses, such as strokes and deep vein thromboses together with recurrent miscarriages. Mycoplasma penetrans, a rare bacterium so far only found in HIV-infected persons, was isolated in the blood and throat of a non-HIV-infected patient with primary antiphospholipid syndrome (whose etiology and pathogenesis are unknown). Yehuda Shoenfeld, along with two colleagues, was awarded the 2005 EULAR (European Union Congress of Rheumatology) Prize for his research in Antiphospholipid Syndrome (APS) - a life-threatening auto-immune disease. |
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