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antiphospholipid antibody syndrome |
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antiphospholipid antibody syndrome
Antiphospholipid syndrome, circulating lupus anticoagulant syndrome Immunology The association of recurrent thromboses–cerebral, repeated spontaneous abortions and renal disease often in ANA-negative
SLE Pts, which may be accompanied by repeated fetal wastage and IgM gammopathy; APA has been defined as a ' thrombophilic disorder in which venous or arterial thrombosis, or both, may occur. The serologic markers are antiphospholipid
antibodies–anticardiolipin antibodies, the lupus anticoagulant, or both'; APAS is characterized by the presence of circulating antiphospholipid antibodies–APA, in particular against cardiolipin–ACA, here used
interchangeably, which overlap with lupus anticoagulants. Cf Lupus anticoagulant. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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