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antimitochondrial antibody

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
antimitochondrial antibody (AMA)
[-mī′tōkon′drē·əl]
an antibody that acts specifically against mitochondria. These antibodies are not normally present in the blood of healthy people.


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Serology for hepatitis A, B and C, toxoplasma IgM, cytomegalovirus IgG and IgM, herpes simplex virus Type 1 and Type 2 IgM, Brucella IgM and IgG, antimitochondrial antibody M2, anti-Sp100, anti-LKM-1, and anti-SLA were all found to be negative.
7) Shintaku and Honda reported that immunohistochemistry with antimitochondrial antibody is highly sensitive and specific for light microscopic identification of mitochondria and superior to routine H&E staining, especially for the detection of isolated oncocytic cells.
Autoimmune hepatitis type 1 and primary biliary cirrhosis are other possible causes of liver dysfunction, but serum antinuclear antibody and antimitochondrial antibody were not detected.
 
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