immune complex

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complex

 [kom´pleks]
1. the sum, combination, or collection of various things or related factors, like or unlike; e.g., a complex of symptoms (see syndrome).
2. a group of interrelated ideas, mainly unconscious, that have a common emotional tone and strongly influence a person's attitudes and behavior.
3. that portion of an electrocardiographic tracing which represents the systole of an atrium or ventricle.
AIDS-related complex (ARC) a complex of signs and symptoms occurring in HIV infection including fever, weight loss, prolonged diarrhea, minor opportunistic infections, lymphadenopathy, and changes in cells of the immune system.
antigen-antibody complex here the complex formed by the noncovalent binding of an antibody and antigen. Complexes of antibodies belonging to certain immunoglobulin classes may activate complement. Called also immune complex.
anti-inhibitor coagulant complex (AICC) a concentrated fraction from pooled human plasma, which includes various coagulation factors. It is administered intravenously as an antihemorrhagic in hemophilic patients with inhibitors to coagulation factor VIII.
atrial complex the P wave of the electrocardiogram, representing electrical activity of the atria. See also ventricular complex.
castration complex in psychoanalytic theory, unconscious thoughts and motives stemming from fear of loss of the genitals as punishment for forbidden sexual desires.
Electra complex libidinous fixation of a daughter toward her father. This term is rarely used, since oedipus complex is generally applied to both sexes.
factor IX complex a sterile, freeze-dried powder consisting of partially purified coagulation factor IX fraction, as well as concentrated factor II, VII, and X fractions, of venous plasma from healthy human donors. It is used in the prophylaxis and treatment of bleeding in patients with hemophilia B, replacement of factor VII in patients deficient in that factor, and treatment of anticoagulant-induced hemorrhage. Administered intravenously.
Ghon complex primary complex (def. 1).
Golgi complex golgi apparatus.
HLA complex the human major histocompatibility complex, which contains the hla antigens.
immune complex antigen-antibody complex.
inclusion complex one in which molecules of one type are enclosed within cavities in the crystalline lattice of another substance.
inferiority complex unconscious feelings of inadequacy, producing shyness or timidity or, as a compensation, exaggerated agressiveness and expression of superiority; based on Alfred Adler's concept that everyone is born with a feeling of inferiority stemming from real or imagined physical or psychological deficiency, with the manner in which the inferiority is handled determining behavior.
interpolated premature ventricular complex a premature ventricular complex that does not interfere with the conduction of the next sinus beat, i.e., it lacks the usual following compensatory pause.
major histocompatibility complex (MHC) the chromosomal region containing genes that control the histocompatibility antigens; in humans it controls the hla antigens.
membrane attack complex (MAC) C5b,6,7,8,9, the five-molecule complex that is the cytolytic agent of the complement system.
Oedipus complex see oedipus complex.
primary complex
1. the combination of a parenchymal pulmonary lesion (Ghon focus) and a corresponding lymph node focus, occurring in primary tuberculosis, usually in children. Similar lesions may also be associated with other mycobacterial infections and with fungal infections.
2. the primary cutaneous lesion at the site of infection in the skin, e.g., chancre in syphilis and tuberculous chancre.
QRS complex a group of waves seen on an electrocardiogram, representing ventricular depolarization. Called also QRS wave. It actually consists of three distinct waves created by the passage of the cardiac electrical impulse through the ventricles and occurs at the beginning of each ventricular contraction. In a normal surface electrocardiogram the R wave is the upward deflection; the first downward deflection represents a Q wave and the final downward deflection is the S wave. The Q and S waves may be extremely weak and sometimes are absent.

One abnormality of the QRS complex is increased voltage resulting from enlargement of heart muscle, which produces increased quantities of electric current. A low-voltage QRS complex may result from toxic conditions of the heart, most commonly from fluid in the pericardium. Pleural effusion and emphysema also can cause a decrease in the voltage of the QRS complex.
VATER complex an association of congenital anomalies consisting of vertebral defects, imperforate anus, tracheoesophageal fistula, and radial and renal dysplasia.
ventricular complex the Q, R, S, and T waves of the electrocardiogram, representing ventricular electrical activity. See also atrial complex.

im·mune com·plex

antigen combined with specific antibody, to which complement may also be fixed. It may precipitate or remain in solution. Frequently associated with autoimmune disease.
Synonym(s): immunocomplex

immune complex

Immunology A molecular aggregate formed between antigens and antibodies. See Immune complex disease.

im·mune com·plex

(i-myūn' kom'pleks)
Antigen combined with a specific antibody, to which complement may also be fixed and may precipitate or remain in solution. Frequently associated with autoimmune disease.

complex

1. the sum or combination of various things, like or unlike, as a complex of clinical signs.
2. that portion of an electrocardiographic tracing that represents the systole of an atrium or ventricle.

antibody-antigen complex
a complex formed by the combining of antibody and antigen. Called also immune complex.
Golgi complex
a complex cellular organelle involved in the synthesis of glycoproteins, lipoproteins, membrane-bound proteins and lysosomal enzymes. See also golgi apparatus.
immune complex
antibody-antigen complex.
major histocompatibility complex (MHC)
see major histocompatibility complex.
multienzyme complex
the bringing together of all of the enzymes involved in a series of reactions such that the product of enzyme A is passed directly to enzyme B and so on to the final product.
olivary nuclear complex
gray matter located in the medulla oblongata dorsal to the pyramidal tracts; an important part of the motor feedback regulatory mechanism.
primary complex
the combination of a parenchymal pulmonary lesion and a corresponding lymph node focus, occurring in primary tuberculosis. Similar lesions may also be associated with other mycobacterial infections and with fungal infections.

immune

1. being highly resistant to a disease because of the formation of humoral antibodies or the development of immunologically competent cells, or both, or as a result of some other mechanism, such as interferon activities in viral infections.
2. characterized by the development of antibodies or cellular immunity, or both, following exposure to antigen.
3. produced in response to antigen, such as immune serum globulin. The essential feature of antibody and cell-mediated immunity is that they are highly antigen specific.

immune adherence
the binding of antibody-antigen-complement complexes to complement receptors found on red blood cells.
immune complex
see antibody-antigen complex.
immune complex disease
disease induced by the deposition of or association with antigen-antibody-complement complexes in the microvasculature of tissues. Fixation of complement component C3 by the complexes initiates inflammation. See also serum sickness, hypersensitivity.
immune complex reaction
type III hypersensitivity (1).
immune deficiency disease
one in which animals have inadequate immune responses and so are more susceptible to infectious disease. The defect may be primary (inherited), or secondary (acquired) which usually develops after birth because of toxins or infectious agents. See also combined immune deficiency syndrome, hypogammaglobulinemia, agammaglobulinemia, inherited parakeratosis, chediak-higashi syndrome and canine granulocytopathy syndrome.
immune hemolysis
see immune-mediated hemolytic anemia (below).
immune interferon
immune modulator
immune reaction
immune response.
immune reaction fever
aseptic fever occurring in anaphylaxis, angioedema.
immune response
the specific response to substances interpreted by the body as not-self, the result being humoral and cellular immunity. The immune response depends on a functioning thymus and the conversion of stem cells to B and T lymphocytes. These B and T lymphocytes contribute to antibody production, cellular immunity and immunological memory. See also humoral immunity.
immune response (Ir) genes
see immune response genes.
immune surveillance
the detection by lymphocytes, especially T lymphocytes, of new antigens, particularly on tumor cells.
immune system
consists of the primary lymphoid organs (thymus and Bursa of Fabricius or its equivalent (bone marrow) in mammals) and secondary lymphoid organs (lymph nodes, spleen and other lymphoid tissue).
immune tolerance
see immunological tolerance.
References in periodicals archive ?
The researchers used three control groups to confirm their findings: 21 of 22 subjects who tested positive for the disease also had the antigen-antibody complex; all 19 controls with other diseases did not have the complex, and four of 12 controls with no rash but with other symptoms, and who tested negative for the disease, had the antigen-antibody complex.
In OvaRex(R) clinical trials to date, activation of immune responses to the antigen-antibody complex (CA125-OvaRex(R) MAb) has been observed in over 50% of OvaRex(R) treated patients.