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antigen-presenting cell
(redirected from Antigen presenting cell)

    Also found in: Wikipedia 0.01 sec.
antigen-presenting cell
n.
A cell, originating in the bone marrow and subsequently found as a dendritic cell in various locations, that facilitates the immune response by holding antigens on its surface and presenting them to lymphocytes.
antigen-presenting cell,
a cell that can break down protein antigens into peptides and present the peptides, in conjunction with major HLA complex class II molecules, on the cell surface, where they can interact with T cell receptors. Macrophages are one type of antigen-presenting cell.


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pDCs produce type I interferons after exposure to conserved viral regions, and these cytokines stimulate the maturation of antigen presenting cells and the induction of antiviral CD8+ T cell, CD4+ T cell, NK cell and B cell responses.
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The immunological implications of TCI are profound as this technique appears to target highly accessible antigen presenting cells (APC) in the skin that can be exploited for a variety of immune outcomes.
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and the international Ludwig Institute for Cancer Research (LICR) have announced a multi-year clinical research collaboration focusing on a series of tumor-associated antigens (TAAs) for use in Celldex's Antigen Presenting Cell (APC) Targeting Technology.
CELLDEX/LUDWIG INST. FORM RESEARCH COLLABORATION by Biotech Business
 
 
 
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