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Antibiotic |
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antibiotic /an·ti·bi·ot·ic/ (-bi-ot´ik) a chemical substance produced by a microorganism, which has the capacity to inhibit the growth of or to kill other microorganisms; antibiotics sufficiently nontoxic to the host are used in the treatment of infectious diseases. broad-spectrum antibiotic one effective against a wide range of bacteria. ß-lactam antibiotic any of a group of antibiotics, including the cephalosporins and the penicillins, whose chemical structure contains a ß ring; they inhibit synthesis of the bacterial peptidoglycan wall.
Antibiotic A chemical substance produced by a microorganism which can inhibit the growth of or kill other microorganisms. Mentioned in: Antiseptics, Antiulcer Drugs, Campylobacteriosis, Cholangitis, Clenched Fist Injury, Enterovirus Infections, Fever of Unknown Origin, Helicobacteriosis, Nasopharyngeal Culture, Ototoxicity, Prophylaxis, Shigellosis, Throat Culture antibiotic, n a substance that combats bacterial infection by killing bacteria or stopping bacterial growth. antibiotic (an´tibīot´ik), n an organic substance produced by one of several microorganisms, especially certain molds, that is capable, in low concentration, of destroying or inhibiting the growth of certain other microorganisms. antibiotic, oral reactions to, n the manifestations on the oral mucous membrane of reactions to antibiotics; characterized by glossitis, angular cheilosis, and/or a hairy tongue. Reactions may result from an imbalance of oral flora produced by the antibiotics or from hypersensitivity to the antibiotics. antibiotic prophylaxis n the use of an antibiotic to protect a patient from an anticipated bacterial invasion associated with a medical or dental invasive procedure, particularly patients with a compromised cardiovascular system and risk of bacterial endocarditis. antibiotic, subgingival placement, n the administration of antimicrobials in the subgingival region to control bacterial infections and manage periodontal disease. antibiotic therapy, n See therapy, antibiotic.
antibiotic 1. destructive of life. 2. a chemical substance produced by a microorganism that has the capacity, in dilute solutions, to kill (biocidal activity) or inhibit the growth (biostatic activity) of other microorganisms. Antibiotics that are sufficiently nontoxic to the host are used as chemotherapeutic agents in the treatment of infectious diseases. See also antimicrobial. 3. used as feed additives to animals as growth promotants. anthracycline a's a group of antibiotics which have a tetracycline ring structure substituted with the sugar daunosamine. Includes the antineoplastic drugs doxorubicin and daunorubicin. antineoplastic antibiotic see antineoplastic. bactericidal antibiotic one that kills bacteria. bacteriostatic antibiotic one that suppresses the growth of bacteria. broad-spectrum antibiotic one that is effective against a wide range of bacteria. antibiotic detection on-farm and prepackaged laboratory tests available for testing farm products and animal tissues and fluids for antibiotic residues. antibiotic drugs the range includes the following groups: penicillin, aminoglycoside, tetracycline, chloramphenicol, macrolide, nitrofuran, cephalosporins, and a miscellaneous group including bacitracin, tyrothricin, polymyxin, colistin. antibiotic feed additives see feed additives. first generation antibiotic one produced as a natural product, e.g. penicillin G. See second generation antibiotic (below). antibiotic food preservation is a satisfactory technique but very strictly controlled because of the problem of residues in the food. Used mostly for the preservation of fish. antibiotic-induced diarrhea see pseudomembranous colitis, acute undifferentiated diarrhea of the horse. antibiotic residue in food in human food of animal origin is a seriously regarded pollution in public health surveillance. The residues may arise from systemic administration, or even after absorption from a local site such as the uterus, but the most serious contamination arises from milk from quarters that have been treated for mastitis. It is essential for the safety of the human population, the financial well-being of the farmer and the professional reputation of the veterinarian that antibacterial withdrawal times are observed. antibiotic resistance see antimicrobial resistance. second generation antibiotic produced by manipulation of the molecular structure of a first generation antibiotic (see above) so that the metabolism and pharmacodynamics of the original compound are significantly altered. antibiotic sensitivity test see antimicrobial sensitivity test. antibiotic therapy antibiotics vary in their absorption from the alimentary tract, requiring some, e.g. streptomycin, to be given parenterally for systemic effect, freedom from toxicity, the range of bacteria against which they are effective, their capacity to stimulate resistance and whether they are bacteriostatic or bactericidal in their effects. Selection of the most suitable antibiotic to suit a particular circumstance may be guided by an antimicrobial sensitivity test, knowledge of the infection present and the price of the drug. In many instances, because of lack of knowledge of the infection present it is necessary to choose an agent with a broad antibacterial spectrum. antibiotic withdrawal, antibiotic withholding see antibacterial withdrawal time. antibiotic adjective Relating to the destruction of living things noun Medtalk 1. An agent obtained directly from a yeast or other organism which is used against a bacterial infection 2. Any agent used to kill or reduce the growth of any infectious agent, including viruses, fungi and parasites. See Drug resistance, Macrolide antibiotic, Polyene antibiotic Molecular biology A substance that interferes with a particular step of cellular metabolism, causing either bactericidal or bacteriostatic inhibition; sometimes restricted to those having a natural biological origin. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Group B streptococcal disease in the era of intrapartum antibiotic prophylaxis. Antibiotic prophylaxis may reduce the incidence of mediastinitis and deep neck abscess. Antibiotic prophylaxis is often required for any procedure that penetrates dental mucosa. |
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