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antineutrophil cytoplasmic antibody
(redirected from Anti-neutrophil cytoplasmic antibody)

    Also found in: Acronyms, Wikipedia 0.01 sec.
antineutrophil cytoplasmic antibody
ANCA Immunology Any autoantibody directed against certain components of granulocytes, myeloid-specific lysosomal enzymes; ANCAs are most commonly found in systemic vasculitides–eg, necrotizing vasculitis, active generalized Wegener's granulomatosis–WG, 84-100% are positive, polyarteritis nodosa, inflammatory conditions of the lung and kidney–eg, crescentic glomerulonephritis, unexplained renal failure, Churg-Strauss syndrome, HIV infection, IBD, drug-induced lupus, SLE, rheumatoid arthritis, and others


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