antineutrophil cytoplasmic antibodies

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antineutrophil cytoplasmic antibodies (ANCA),

autoantibodies found in some autoimmune diseases, recognized by their reactivity with cytoplasmic antigens in neutrophils; two groups are recognized: c-ANCA, reacting with proteinase 3, is found in polyangiitis and Churg-Strauss syndrome; p-ANCA, reacting with myeloperoxidase is found in Wegener granulomatosis.
References in periodicals archive ?
False positive' perinuclear and cytoplasmic anti-neutrophil cytoplasmic antibody results leading to misdiagnosis of Wegener's granulomatosis and/or microscopic polyarteritis.
A new type of perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) in ulcerative colitis but not in Crohn's disease.
The chapter on autoimmune disease and serology was not included in the current edition, and related topics such as anti-neutrophil cytoplasmic antibody, anti-nuclear antibody, dermatomyositis, Raynaud disease, and mixed connective tissue disease were not identified in the index.