muscarinic antagonist

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mus·ca·rin·ic an·tag·o·nist

drugs that bind with muscarinic cholinergic receptors but do not activate them, thus preventing access to acetylcholine; examples include atropine, scopolamine, propantheline, and pirenzepine.
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Other anti-muscarinic agents such as pirenzipine have also been trialled with promising results, although, unlike other interventions, they do not appear to impact upon axial length growth, which poses an interesting question regarding the precise mechanism of this drug.
To calculate the market size, the report considers the revenue generated from the sales of various generic and branded therapies used in the treatment of overactive bladder, which include: -- Anti-muscarinic Agent -- Beta-3-Adrenergic Receptor Agonist TechNavio's report, Global Overactive Bladder Therapeutics Market 2014-2018, has been prepared based on an in-depth market analysis with inputs from industry experts.
used in combination with anti-muscarinic agents and beta2-agonists.
18] In men with predominant storage LUTS, anti-muscarinic monotherapy is well tolerated and improves symptoms such as bedwetting and urgency urinary incontinence.
Efficacy of mirabegron in patients with and without prior anti-muscarinic therapy for overactive bladder (OAB): Post-hoc analysis of a prospective, randomised European-Australian phase III trial.
Martin-Latry showed that 'heat stroke' cases were much more likely than controls to have been taking anti-muscarinic drugs (OR 6.
This can be treated with anti-muscarinic drugs prescribed by your GP.
Of the eight trials, two were placebo-controlled dose selection trials, four were placebo-controlled 1-year trials primarily designed to evaluate the efficacy of Daliresp on COPD exacerbations, and two were 6-month trials with Daliresp as add-on therapy to a long-acting beta-agonist or long-acting anti-muscarinic which provide safety support for the Daliresp COPD program.
showing the synergistic effect of RPL554 and the anti-muscarinic drugs
To the best of our knowledge, there have been few reports on the efficacy and tolerability of combined anti-muscarinic medication targeted for adults with idiopathic OAB.
This is an anti-muscarinic drug with short-lasting effect on the pupil (mydriasis) and on accommodation (cycloplegia) at the 1% concentration.
These new data also suggest that DAS181 might be useful as a novel, once-daily anti-muscarinic agent for the management of patients with diseases such as asthma and COPD, and an ongoing clinical trial is assessing this possibility," added Dr.