antihypertensive

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antihypertensive

 [an″te-, an″ti-hi″per-ten´siv]
effective against hypertension.
antihypertensive agent an agent that reduces high blood pressure; there are many different types of drugs that do this. diuretics inhibit the reabsorption of sodium in the renal tubules, causing an increase in urinary excretion of sodium and a decrease in the plasma volume and extracellular fluid volume. Drugs that act on adrenergic control of blood pressure include beta-adrenergic blocking agents such as propranolol, which act at beta-adrenergic receptors in the heart and kidneys to reduce cardiac output and renin secretion, and others such as methyldopa that act on alpha-adrenergic mechanisms in the central or sympathetic nervous system to reduce peripheral vascular resistance. vasodilators act directly on the arterioles to produce the same effect. Almost every case of hypertension can be controlled by one of these drugs or a combination of them. The proper combination is determined by the response of the individual patient. In some cases several drugs must be tried before the right combination is found.
Patient Education. Instruction of the patient and significant others is an essential part of antihypertensive therapy. Learning objectives are based on the patient's particular regimen of drug therapy, allowance of sodium intake, and other dietary restrictions, such as a low-calorie diet to combat obesity.

Some antihypertensive drugs can produce acute hypotensive reactions. The patient will need to know how to prevent a hypotensive reaction and what measures to take should such a reaction occur.

Prevention of a hypotensive reaction includes avoiding hot baths and sudden immobility after exercise, both of which promote vasodilation and a lowering of arterial pressure. The patient also should be aware of the effect of sudden changes in position that can precipitate an attack of orthostatic hypotension. Pooling of blood in the lower limbs can divert it from the brain and other vital organs. This can sometimes be avoided by moving about frequently instead of standing motionless for long periods of time. Elastic stockings also help promote venous return from the legs and help prevent fainting from decreased cerebral blood supply.

Acute hypotension can be serious, but milder hypotensive reactions with faintness and weakness can be relieved at home if the patient lies down and elevates his lower extremities above the level of his head and flexes the thigh muscles to encourage the flow of blood from his feet and legs to his brain.

The patient on a diuretic that is not potassium-sparing will need instruction on the symptoms of potassium deficit, how to avoid potassium depletion, and when to notify the doctor should hypokalemia occur.

Limitation of sodium intake can be very confusing and emotionally stressful to the uninstructed patient. In order to comply with the prescribed restriction of sodium the patient will need to know about satisfying substitutes and alternative seasonings for food, to be aware of the necessity of reading labels carefully when buying prepared food and over-the-counter medications, and to recognize the relationship between sodium and high blood pressure and the reasons why high sodium intake is harmful to health and well-being.

an·ti·hy·per·ten·sive

(an'tē-hī-per-ten'siv),
Indicating a drug or mode of treatment that reduces the blood pressure of hypertensive patients.

antihypertensive

/an·ti·hy·per·ten·sive/ (-ten´siv) counteracting high blood pressure, or an agent that does this.

antihypertensive

(ăn′tē-hī′pər-tĕn′sĭv, ăn′tī-)
adj.
Reducing or controlling high blood pressure.
n.
An antihypertensive drug.

antihypertensive

[-hī·pərten′siv]
1 pertaining to a substance or procedure that reduces high blood pressure.
2 an antihypertensive agent. Various drugs achieve their antihypertensive effect by depleting tissue stores of catecholamines in peripheral sites, by stimulating pressor receptors in the carotid sinus and heart, by blocking autonomic nerve impulses that constrict blood vessels, by stimulating central inhibitory alpha2 receptors, or by causing vasodilation. Thiazides and other diuretic agents inhibit the reabsorption of sodium in the renal tubules, increasing urinary excretion of sodium and decreasing plasma and extracellular fluid volume, decreasing blood volume. Drugs that act on adrenergic control of blood pressure include beta-adrenergic blocking agents, which act at beta-adrenergic receptors in the heart and kidneys to reduce cardiac output and renin secretion; and others that act on alpha-adrenergic mechanisms in the central or sympathetic nervous system to reduce peripheral vascular resistance. Vasodilatators act directly on the arterioles to produce the same effect. Other drugs used to treat hypertension are HCl, angiotensin-converting enzyme inhibitors, nonnitrate vasodilators, calcium channel blockers, and angiotensin receptor blockers. Almost every case of hypertension can be controlled by one of these drugs or a combination of them. The proper combination is determined by the response of the individual. In some cases, several drugs must be tried before the right combination is found. Compare antihypotensive.

antihypertensive

adjective Referring to an agent or mechanism that counters hypertension.

noun An agent used to manage hypertension.

antihypertensive

adjective Referring to an agent or mechanism that reduces HTN noun An agent used to manage HTN

an·ti·hy·per·ten·sive

(an'tē-hī-pĕr-ten'siv)
Indicating a drug or mode of treatment that reduces the blood pressure of people with hypertension.

antihypertensive

1. Acting against high blood pressure (HYPERTENSION).
2. A drug used in the treatment of high blood pressure.

Antihypertensive

Used to describe drugs or treatments designed to control hypertension, or high blood pressure.
Mentioned in: Hyperaldosteronism

antihypertensive,

n a medicine or substance that reduces blood pressure.

an·ti·hy·per·ten·sive

(an'tē-hī-pĕr-ten'siv)
Indicating a drug or treatment that reduces the blood pressure of hypertensive patients.

antihypertensive

acting to reduce tension; in medical terms, usually referring to elevated blood pressure. Drugs used for this purpose include diuretics, β-adrenergic antagonists, and vasodilators.
References in periodicals archive ?
After several weeks the patient's symptoms had improved and she was weaned to a maintenance dose of anti-hypertensive medication; 6 months later she was able to stop all anti-hypertensive medications.
If you've been taking them for nine years or more, you may want to speak with your doctor about a different anti-hypertensive.
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A double-blind, randomized, parallel and active-controlled clinical study was conducted to evaluate the anti-hypertensive effect as well as the tolerability of Olive leaf extract in comparison with Captopril in patients with stage-1 hypertension.
Summary: RIYADH: The Prince Salman Heart Center at King Fahd Medical City has announced the first use in Saudi Arabia of "Renal DeNervation" with the "Medtronic Symplicity" Catheter System to treat patients with resistant hypertension, which is defined as high blood pressure despite treatment with three or more anti-hypertensive medications.
When he arrived in the recovery room, he was given anti-hypertensive medications to control his blood pressure.
Excellent clinical trial outcome data prove that lowering BP with several classes of currently available anti-hypertensive drugs, including angiotensin converting enzyme (ACE) inhibitors, angitoensin-receptor blockers (ARBS), [alpha]-blockers, calcium channel blockers (CCBS) and thiazide-type diuretics, will all reduce the complications of hypertension (Chobanian et al.
Alcohol can also interact with anti-hypertensive drugs enhancing their function.
Lahore, October 05, 2010 (Frontier Star): A spokesman of Health Department Punjab has clarified a news item published in a Section of Press and said that the department has been providing all necessary medicines to the flood effected districts including anti-biotic, anti-allergy, anti-hypertensive, ear and eye drops and skin ointments/ creams.
Both groups were treated with anti-hypertensive medication Ramipril and one group of 29 patients took Pycnogenol in addition to the Ramipril.
In 16 chapters on basic mechanisms that have clinical implications, international scientists discuss the related renin-angiotensin-aldosterone system (RAAS) which plays a critical role in hypertension, failing heart tissue, metabolic syndrome, and type II diabetes; the role of newly discovered factors such as angiotensin-converting enzyme ACE-2; and the role of kinins in, and effect of salt intake on, the anti-hypertensive effect of ACE inhibitors.
the injured plaintiff's blood pressure was around 170/100, at which point Hydralazine, an anti-hypertensive agent was first administered to her.