Of those, 12 had received anti-estrogen
therapy and 28 had not, reported Dr.
Summary: TEHRAN (FNA)- Findings of a new study, presented at the CTRC-AACR San Antonio Breast Cancer Symposium, revealed that anti-estrogens
as therapy for breast cancer may also reduce the risk of death from lung cancer.
If estrogen and/or progesterone receptors are present, then it is likely that the patient will be treated with anti-estrogen
therapy, also called hormonal therapy.
For this reason, anti-estrogen
drugs such as tamoxifen and aromatase inhibitors have come to the forefront in the fight against hormone-dependent breast cancer.
Translated" from basic research in molecular biology, these approaches include new/ improved anti-estrogen
and targeted chemotherapeutic and biologic therapies.
a professor in the Department of Family and Preventive Medicine at the University of California in San Diego, reported that women whose breast cancer came back after treatment had almost twice as much estrogen in their blood than did women who remained cancer-free--despite treatment with anti-estrogen
drugs in most of the women.
Environmental chemicals with estrogenic activity are probably the most well studied however chemicals with anti-estrogen
, androgen, anti-androgen, progesterone, or thyroid-like activity have also been identified.
was described as blocking classic ER-mediated actions in vivo (Johnson et al.
These cancers rely on estrogen to grow, so anti-estrogen
therapies aim to cut off their fuel supply.
In 1999, Aromasin was approved in Europe through Mutual Recognition Procedure for treatment of advanced breast cancer after prior anti-estrogen
The problem is that we don't know if it acts as an estrogen Or an anti-estrogen
," said Dr.
Prof Nicholson added: "Tamoxifen is an anti-estrogen
drug, so it blocks off the amount of estrogen in the body.