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aromatase inhibitor
(redirected from Anti-estrogen)

   Also found in: Wikipedia 0.07 sec.
aromatase inhibitor
n.
A drug that inhibits tumor growth, especially breast cancer, by inhibiting the enzyme aromatase and thereby lowering estrogen levels in the blood or in tumor tissues.


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This anti-estrogen was described as blocking classic ER-mediated actions in vivo (Johnson et al.
These cancers rely on estrogen to grow, so anti-estrogen therapies aim to cut off their fuel supply.
It acts as an estrogen on some tissues (like bone), but as an anti-estrogen on others (like the breast), and that can increase bone density while lowering breast cancer risk.
 
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