antiandrogen

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androgen

 [an´dro-jen]
any steroid hormone that promotes male secondary sex characters. The two main androgens are androsterone and testosterone. Called also androgenic hormone. adj., adj androgen´ic. 

The androgenic hormones are internal endocrine secretions circulating in the bloodstream and manufactured mainly by the testes under stimulation from the pituitary gland. To a lesser extent, androgens are produced by the adrenal glands in both sexes, as well as by the ovaries in women. Thus women normally have a small percentage of male hormones, in the same way that men's bodies contain some female sex hormones, the estrogens. Male secondary sex characters include growth of the beard and deepening of the voice at puberty. Androgens also stimulate the growth of muscle and bones throughout the body and thus account in part for the greater strength and size of men as compared to women.
androgen insensitivity syndrome complete androgen resistance.

an·ti·an·dro·gen

(an'tē-an'drō-jen),
Any substance capable of preventing full expression of the biologic effects of androgenic hormones on responsive tissues, either by producing antagonistic effects on the target tissue, as estrogens do, or by merely inhibiting androgenic effects, such as by competing for binding sites at the cell surface.

antiandrogen

/an·ti·an·dro·gen/ (-an´dro-jen) any substance capable of inhibiting the biological effects of androgens.

antiandrogen

(ăn′tē-ăn′drə-jən, ăn′tī-)
n.
A substance that inhibits the biological effects of androgenic hormones.

antiandrogen

Endocrinology A hormone or other agent–eg, megestrol acetate, spironolactone, flutamide, nilutamide, and cimetidine, which interferes with androgen function by competitively inhibiting androgen binding to cognate receptors at the target organ and is either biologically inert or functionally very weak; these compounds are used to manage androgen-dependent CAs–♂ breast and prostate, hirsutism, acne

Antiandrogen

A substance that blocks the action of androgens, the hormones responsible for male characteristics. Used to treat prostate cancers that require male hormones for growth.
Mentioned in: Prostate Cancer

antiandrogen

any substance capable of inhibiting the biological effects of androgenic hormones.
References in periodicals archive ?
In April 2012, Hygeia assigned the patents for the anti-androgens -- originally developed at Yale Medical School -- that treat acne, excess facial hair and hair loss to a subsidiary called Canterbury Labs.
It has been criticised by the Council of Europe's Anti-torture Committee (CPT) which said that, as a matter of principle, anti-androgen treatment should only be given "on a voluntary basis and following a thorough psychiatric and medical assessment".
Co-incubation with the anti-androgen flutamide (FLU) reversed the TC-induced stimulation of PSA secretion.
Emergence of metastatic hormone-refractory disease in prostate cancer after anti-androgen therapy.
A(DIANETTE) Co-Cyprindiol is an established form of the combined contraceptive, but in place of progesterone it contains an anti-androgen, Cyproterone, which decreases the production of testosterone, making it good at treating acne in girls.
Environmental chemicals with estrogenic activity are probably the most well studied however chemicals with anti-estrogen, androgen, anti-androgen, progesterone, or thyroid-like activity have also been identified.
They may only indicate hyperandrogenism, which can result from several conditions and can be treated with anti-androgen medications.
We think all of these findings fit with the idea that DEHP is an anti-androgen.
For the first time, GPs will be able to prescribe anti-androgen drugs to take away perverts' sexual urges after their release from jail.
The anti-androgen action of this medication is confined almost entirely to the scalp and prostate.
This drug is a new-generation anti-androgen treatment that can prolong life for men who have failed hormone and chemo therapies.
a biotech start-up based in Holden that's trying to develop a special form of an anti-androgen that can treat acne, excess facial hair and hair loss, and an estrogen that can treat urogenital and skin problems that face menopausal women.