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anthracycline |
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anthracycline /an·thra·cy·cline/ (-si´klēn) a class of antineoplastic antibiotics produced by Streptomyces peucetius and S. coeruleorubidus, including daunomycin and doxorubicin. anthracycline a class of antibiotics isolated from cultures of Streptomyces peucetius; it includes the antineoplastic agents daunomycin and doxorubicin. See also anthracycline antibiotic. anthracycline Oncology A chemotherapeutic used in leukemia to prevent cell division Adverse effects Dose-dependent stomatitis, N&V and BM suppression which 'maxes' at ± 10 days; alopecia is normal; extravasation at IV
injection site causes severe, protracted ulcers and necrosis. See Chemotherapy, Daunorubicin, Doxorubicin, Idarubicin. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Researchers are recruiting women who have already been treated with the chemotherapy drugs Taxol or Taxotere, and an anthracycline drug such as Adriamycin, but have relapsed. In fact, after patients in breast cancer chemotherapy are given the first drug, anthracycline, only half of the patients respond to the next drug Taxol, Parissenti explains. has received approval to market its proprietary anti-cancer drug, PAXENE (paclitaxel), in Canada for the treatment of AIDS-related Kaposi's sarcoma in patients who have failed prior liposomal anthracycline therapy. |
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