ANXA1

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ANXA1

A gene on chromosome 9q21.13 that encodes annexin 1, a calcium/phospholipid-binding protein that promotes membrane fusion and is involved in exocytosis. Annexin 1 regulates phospholipase A2 activity and thus may have anti-inflammatory activity.
References in periodicals archive ?
Immunohistochemistry showed positivity with CD20, annexin A1, and DBA44 (B lymphocyte markers).
HCL is characterized by expression of B-cell markers (CD19, CD20, CD22) as well as CD11c, CD25, CD103, DBA44, and annexin A1 (2).
667e +05 Annexin A1 (lipocortin 1); Lipocortin 1 (Homo sapiens) Accession Number: 4502101 Endoplasmic 28994-29033/6.
2]-Macroglobulin IPI00478003 639 Annexin A1 IPI00218918 297 Annexin A2 IPI00455315 116 Annexin A3 IPI00024095 85 Annexin A5 IPI00329801 268 Antithrombin III IPI00032179 18 Apolipoprotein A-I IPI00021841 593 Apolipoprotein E IPI00021842 51 Arginase 1 IPI00038356 43 [[beta].
In this study we investigated the in vitro effects of resveratrol on the apoptotic cascades in human promyelocyte leukemia (HL-60) cells and first demonstrated that growth arrest- and DNA damage-induced gene 45 [alpha] (GADD45 [alpha]) and annexin A1 are involved in the apoptosis effects of resveratrol in these cells.
Nitrocellulose membranes (Millipore, Bedford, MA, USA) were incubated overnight at 4[degrees]C with mouse annexin A1 monoclonal antibody or rabbit polyclonal antibodies against human Bcl-2, Bax, GADD45 [alpha] or cleaved caspase 3.
The protein expression of annexin A1 was increased with resver-atrol treatment (Fig.
The levels of GADD45cx and annexin A1 are also found to increase with the treatment of resveratrol.