Ann Arbor classification

Ann Arbor staging

A system for staging Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) and guiding therapy. Clinical data is added based on A (absence) or B (presence) of associated symptoms—e.g., night sweats, fever or weight loss of > 10%; other symptoms of HL/NHL include lethargy, fatigability, anorexia and pruritus.

Ann Arbor classification

A system for staging Hodgkin's disease and guiding therapy; clinical data is added based on A–absence or B–presence of associated symptoms–eg, night sweats, fever or weight loss of > 10%; other Sx of Hodgkin's disease include lethargy, fatigability, anorexia, pruritus. See Hodgkin's disease.
Ann Arbor classification
  1. A single involved lymphoid region, organ or site
  2. 2+ involved lymphoid regions, or one extralymphoid site and a lymphoid region on the same side of the diaphragm
  3. Lymphoid regions involved on both sides of the diaphragm, ± accompanied by local ized involvement of extralymphatic organs or spleen
  4. Disseminated involvement of 1+ extralymphatic organs or tissues, with/without asso ciated lymphadenopathy
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Ann Arbor classification

A method of deciding on the stage to which any case of HODGKIN'S DISEASE has progressed. Staging is important in deciding the best treatment and in determining the outlook (prognosis). In Stage I only one lymph node or one extra-lymphatic site is involved. In Stage IV, tissues such as bone marrow and liver are affected.
References in periodicals archive ?
20) There is no allowance for the staging of multiple tumors in the Ann Arbor classification.
Such involvement cannot be documented using the Ann Arbor classification system.
Three systems have been used to classify paranasal sinus lymphomas: the Ann Arbor classification, (14) the international histologic classification, (15) and the revised European-American lymphoma (REAL) classification (16); the Ann Arbor system is the most widely used (table 1).
Ann Arbor classification of lymphomas (14) Stage I Involves 1 ganglionic chain (I) or localized involvement of 1 extralymphatic organ (IE) Stage II Involves 2 or more ganglionic chains ipsilateral to the diaphragm (II) or involves 1 extralymphatic site and 1 or more ganglionic chains ipsilateral to the diaphragm (IIE) Stage III Involves various ganglionic chains on both sides of the diaphragm (III), possibly associated with extralymphatic sites (IIIE), the spleen (IIIS), or both (IIIES) Stage IV Involves various extralymphatic sites with or without ganglionic involvement or 1 isolated site associated with distal ganglions Type A Without systemic symptoms Type B With systemic symptoms Table 2.

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