Anitschkow cell | definition of Anitschkow cell by Medical dictionary
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a large mononuclear cell found in connective tissue of the heart wall in inflammatory conditions, especially in the Aschoff body. The ovoid nucleus contains a central chromatin mass appearing as a wavy bar in longitudinal section.A cell with an elongated vesicular nucleus, central wavy chromatin and finger-like projections to the nuclear membrane. Caterpillar cells are variants of Anitschkow cardiac histiocytes—‘owl eye’ cells—aggregates of which are termed Aschoff nodules
car·di·ac his·ti·o·cyte (kahr'dē-ak his'tē-ō-sīt)
A large mononuclear cell found in connective tissue of the heart wall in inflammatory conditions, especially in the Aschoff body.
Synonym(s): Anitschkow cell
, Anitschkow myocyte
Anitschkow, (Anichkov), Nikolai, Russian pathologist, 1885-1964.
- a large mononuclear cell found in connective tissue of the heart wall in inflammatory conditions. Synonym(s): Anitschkow myocyte
; cardiac histiocyte
large mononuclear cells with an undulating, ribbon-like formation of nuclear chromatin. These 'caterpillar cells' are found in myocardium and thought to be macrophages or attempts at myofiber regeneration. Called also Anitschkow myocytes.
References in periodicals archive
27) Acute rheumatic heart disease can result in the formation of granulomatous lesions known as Aschoff bodies, which tend to be perivascular in location and may contain enlarged macrophages with nuclear chromatin condensed into a wavy ribbon resembling a caterpillar, that is, Anitschkow cells
Larger mononuclear cells called Anitschkow cells
may be seen within the nodule and, on cut section, bear an owl-eye appearance.