| Dictionary, Encyclopedia and Thesaurus - The Free Dictionary 1,764,263,258 visitors served. |
|
Dictionary/ thesaurus | Medical dictionary | Legal dictionary | Financial dictionary | Acronyms | Idioms | Encyclopedia | Wikipedia encyclopedia | ? |
angiotensin II receptor antagonist |
Also found in: Acronyms, Wikipedia | 0.03 sec. |
|
angiotensin II receptor antagonist Pharmacology Any of a family of agents-eg losartan and valsartan, which block the binding of angiotensin II–A-II to its cognate cell membrane receptors–AT1, AT2, and others;
1st generation ARAs included the sartan family of agents, which only block AT1, interacting with the amino acids in the transmembrane domains, blocking the binding of A-II to AT1; an alternative to ACEI therapy for
Pts with CHF; unlike ACEIs, ARAs do not interfere with bradykinin and prostaglandin metabolism, interference which has been linked to some of the adverse effects of ACEI therapy, particularly to cough and angioedema. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
|
| ? Mentioned in | ? References in periodicals archive | ||
|---|---|---|---|
| It is indicated for patients
with type 2 diabetes with the action of improving insulin resistance,
and TAK-536 is a novel angiotensin receptor blocker (ARB) discovered by
Takeda currently under development for treatment of hypertension in the
U. An angiotensin receptor blocker (ARB) discovered by Takeda, TAK-491
helps lower blood pressure by suppressing the action of vasopressor
hormone Angiotensin II. Such genetic differences help explain the fact that drugs like ACE
inhibitors and angiotensin receptor blockers often don't work as
well in blacks. |
| Medical Dictionary |
| Free Tools: |
For surfers:
Free toolbar & extensions |
Word of the Day |
Help
For webmasters: Free content | Linking | Lookup box | Double-click lookup | Partner with us |
|---|