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angiotensin II receptor antagonist
(redirected from Angiotensin receptor blocker)

   Also found in: Acronyms, Wikipedia 0.01 sec.
angiotensin II receptor antagonist
Pharmacology Any of a family of agents-eg losartan and valsartan, which block the binding of angiotensin II–A-II to its cognate cell membrane receptors–AT1, AT2, and others; 1st generation ARAs included the sartan family of agents, which only block AT1, interacting with the amino acids in the transmembrane domains, blocking the binding of A-II to AT1; an alternative to ACEI therapy for Pts with CHF; unlike ACEIs, ARAs do not interfere with bradykinin and prostaglandin metabolism, interference which has been linked to some of the adverse effects of ACEI therapy, particularly to cough and angioedema.


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There are indeed two common types of blood pressure medicines which inhibit the renin-angiotensin system, ACE-inhibitors like Lisinopril, and angiotensin receptor blockers (ARBs) like Diovan.
COOPERATE study The COOPERATE study reported that progression of chronic kidney disease was retarded to a greater extent with dual blockade of the renin-angiotensin system (RAS) compared with either an ACE inhibitor or angiotensin receptor blocker (ARB) alone.
The most common types of blood pressure medicines doctors prescribe are diuretics, angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), beta blockers, and calcium channel blockers.
 
 
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Angiotensin I-Converting Enzyme
Angiotensin I-Converting Enzyme Activity
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Angiotensin II receptor antagonist
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Angiotensin II Receptor, Type 2
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