androgen insensitivity syndrome

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Related to Androgen insensitivity: Partial androgen insensitivity syndrome

androgen

 [an´dro-jen]
any steroid hormone that promotes male secondary sex characters. The two main androgens are androsterone and testosterone. Called also androgenic hormone. adj., adj androgen´ic. 

The androgenic hormones are internal endocrine secretions circulating in the bloodstream and manufactured mainly by the testes under stimulation from the pituitary gland. To a lesser extent, androgens are produced by the adrenal glands in both sexes, as well as by the ovaries in women. Thus women normally have a small percentage of male hormones, in the same way that men's bodies contain some female sex hormones, the estrogens. Male secondary sex characters include growth of the beard and deepening of the voice at puberty. Androgens also stimulate the growth of muscle and bones throughout the body and thus account in part for the greater strength and size of men as compared to women.
androgen insensitivity syndrome complete androgen resistance.

an·dro·gen re·sis·tance syn·dromes

a class of disorders associated with 5α-steroid reductase deficiency, testicular feminization, and related disorders. Compare: steroid 5α-reductase, Reifenstein syndrome, infertile male syndrome, testicular feminization syndrome.

androgen insensitivity syndrome

n.
An inherited condition in which the body cells are completely or partially unable to respond to androgens, resulting, in the complete form, in a person with an XY karyotype developing typical female external genitalia but usually no uterus, a short vagina, and undescended or partially descended testes. People with mild or partial forms are infertile and have a variety of phenotypes.

an·dro·gen re·sis·tance syn·dromes

(an'drŏ-jen rĕ-zis'tăns sin'drōmz)
A class of disorders associated with 5α-steroid reductase deficiency, testicular feminization, and related disorders.
Compare: Reifenstein syndrome, testicular feminization syndrome
Synonym(s): androgen insensitivity syndrome.
References in periodicals archive ?
Overall in 46 XY DSD patients a definitive diagnosis is made in less than 50% of patients and among diagnosed cases partial androgen insensitivity syndrome is the most common cause20.
Androgen insensitivity syndrome: a survey of diagnostic procedures.
Partial androgen insensitivity and Reifenstein's syndrome: clinical, endocrine and molecular correlates and in vivo response to high-dose testosterone.
Androgen insensitivity syndrome is extremely distressing to the concerned individuals and requires sympathetic handling.
The women were all born with androgen insensitivity syndrome (AIS), which means they have XY, or male, chromosomes, but are either partially or completely insensitive to the sex hormone testosterone.
A small sampling of topics: thyroid hormone transporters and resistance, clinical and molecular aspects of androgen insensitivity, pseudohypoaldosteronism, current issues on molecular diagnosis of GH signaling defects, and human congenital perilipin deficiency and insulin resistance.
TORONTO -- Teenagers with complete androgen insensitivity syndrome need to be told that they are at high risk for sexual dysfunction, Dr.
INTRODUCTION: Androgen insensitivity (testicular feminization) syndrome is a rare inherited form of male pseudohermaphroditism that occurs in phenotypically normal woman with adequate breast development, normal external genitalia, a vagina of variable depth, absent uterus, and sparse or absent pubic hair and axillary hair.
He discusses (and shows home pages) from such sites as Organisation Intersex International and Androgen Insensitivity Syndrome Support Group.
The subjects of this two-part documentary suffered from conditions such as Klinefelter's Syndrome or Complete Androgen Insensitivity Syndrome, or they had both male and female physical/ psychological characteristics.

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