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antiandrogen
(redirected from Androgen antagonists)

    Also found in: Wikipedia 0.01 sec.
antiandrogen /an·ti·an·dro·gen/ (-an´dro-jen) any substance capable of inhibiting the biological effects of androgens.
an·ti·an·dro·gen (nt-ndr-jn, nt-)
n.
A substance that prevents expression of biological effects of androgenic hormones on responsive tissues.
Antiandrogen
A substance that blocks the action of androgens, the hormones responsible for male characteristics. Used to treat prostate cancers that require male hormones for growth.
Mentioned in: Prostate Cancer
antiandrogen
any substance capable of inhibiting the biological effects of androgenic hormones.
antiandrogen
Endocrinology A hormone or other agent–eg, megestrol acetate, spironolactone, flutamide, nilutamide, and cimetidine, which interferes with androgen function by competitively inhibiting androgen binding to cognate receptors at the target organ and is either biologically inert or functionally very weak; these compounds are used to manage androgen-dependent CAs–♂ breast and prostate, hirsutism, acne


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All test systems showed that bicalutamide and hydroxyflutamide act as potent androgen antagonists (Ma et al.
Interlaboratory comparison of four in vitro assays for assessing ... by Soto, Ana M. / Environmental Health Perspectives
This modified system was successfully used by several investigators for assaying androgen antagonists (Peers et al.
OECD validation of the Hershberger assay in Japan: phase 2 dose ... by Owens, William / Environmental Health Perspectives
Calculated properties of dihydrotestosterone (DHT) in relation to fenitrothion and known androgen antagonists.
Interaction of organophosphate pesticides and related compounds with ... by Richard, Ann M. / Environmental Health Perspectives
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