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antiandrogen |
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antiandrogen /an·ti·an·dro·gen/ (-an´dro-jen) any substance capable of inhibiting the biological effects of androgens.
Antiandrogen A substance that blocks the action of androgens, the hormones responsible for male characteristics. Used to treat prostate cancers that require male hormones for growth. Mentioned in: Prostate Cancer antiandrogen any substance capable of inhibiting the biological effects of androgenic hormones. antiandrogen Endocrinology A hormone or other agent–eg, megestrol acetate, spironolactone, flutamide, nilutamide, and cimetidine, which interferes with androgen function by competitively inhibiting androgen binding to cognate receptors
at the target organ and is either biologically inert or functionally very weak; these compounds are used to manage androgen-dependent CAs–♂ breast and prostate, hirsutism, acne How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ? Mentioned in | ? References in periodicals archive | |
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All test systems showed that bicalutamide and hydroxyflutamide act
as potent androgen antagonists (Ma et al. This modified system was successfully used
by several investigators for assaying androgen antagonists (Peers et al. Calculated properties of dihydrotestosterone (DHT) in
relation to fenitrothion and known androgen antagonists. |
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