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antiandrogen
(redirected from Androgen antagonist)

    Also found in: Wikipedia 0.03 sec.
antiandrogen /an·ti·an·dro·gen/ (-an´dro-jen) any substance capable of inhibiting the biological effects of androgens.
an·ti·an·dro·gen (nt-ndr-jn, nt-)
n.
A substance that prevents expression of biological effects of androgenic hormones on responsive tissues.
Antiandrogen
A substance that blocks the action of androgens, the hormones responsible for male characteristics. Used to treat prostate cancers that require male hormones for growth.
Mentioned in: Prostate Cancer
antiandrogen
any substance capable of inhibiting the biological effects of androgenic hormones.
antiandrogen
Endocrinology A hormone or other agent–eg, megestrol acetate, spironolactone, flutamide, nilutamide, and cimetidine, which interferes with androgen function by competitively inhibiting androgen binding to cognate receptors at the target organ and is either biologically inert or functionally very weak; these compounds are used to manage androgen-dependent CAs–♂ breast and prostate, hirsutism, acne


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? Mentioned in ? References in periodicals archive
 
Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist.
Acquisition of androgen independence by human prostate epithelial ... by Waalkes, Michael P. / Environmental Health Perspectives
2002), although BPA acts as an androgen antagonist in the presence of the wild-type androgen receptor (Lee et al.
An extensive new literature concerning low-dose effects of bisphenol ... by Hughes, Claude / Environmental Health Perspectives
For example, an androgen antagonist may oppose the effects of an estrogen agonist on the human pituitary because both androgens and estrogens inhibit luteinizing hormone secretion.
Organochlorine pesticides and male genital anomalies in the child ... by Eskenazi, Brenda / Environmental Health Perspectives
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