| Dictionary, Encyclopedia and Thesaurus - The Free Dictionary 1,730,087,087 visitors served. |
|
Dictionary/ thesaurus | Medical dictionary | Legal dictionary | Financial dictionary | Acronyms | Idioms | Encyclopedia | Wikipedia encyclopedia | ? |
anastrozole |
Also found in: Wikipedia | 0.02 sec. |
|
anastrozole /anas·tro·zole/ (ah-nas´trah-zōl″) an antineoplastic used for treatment of advanced breast carcinoma in postmenopausal women. anastrozole, a nonsteroidal aromatase inhibitor. indication It is prescribed in the treatment of advanced breast cancer for postmenopausal women whose disease has not responded to treatment with tamoxifen. contraindication The drug is usually effective only in patients with estrogen-dependent tumors. adverse effects The side effects most often reported include diarrhea, fatigue, nausea, headache, hot flashes, and back pain. anastrozole Warning - High-alert drug! Arimidex Pharmacologic class: Nonsteroidal aromatase inhibitor Therapeutic class: Antineoplastic Pregnancy risk category D ActionReduces serum estradiol levels with no significant effect on adrenocorticoid or aldosterone level; decreases stimulating effect of estrogen on tumor growth AvailabilityTablets: 1 mg ⊘Indications and dosages ➣ Postmenopausal women with hormone receptor-unknown or hormone receptor-positive advanced breast cancer or with advanced breast cancer after tamoxifen therapy; adjuvant treatment for hormone receptor-positive breast cancer Adults: 1 mg P.O. daily Contraindications• Pregnancy PrecautionsUse cautiously in: Administration• Verify that patient isn't pregnant before giving drug.
Adverse reactionsCNS: headache, weakness, dizziness, depression, paresthesia, lethargy CV: chest pain, peripheral edema, vasodilation, hypertension, thromboembolic disease EENT: pharyngitis GI: nausea, vomiting, diarrhea, constipation, abdominal pain, anorexia, dry mouth GU: vaginal bleeding, leukorrhea, vaginal dryness, pelvic pain Musculoskeletal: bone or back pain, muscle weakness Respiratory: dyspnea, cough Skin: rash Other: food distaste, weight gain, swelling, hot flashes, flulike symptoms, tumor flare InteractionsDrug-diagnostic tests. Hepatic enzymes, low-density lipoproteins, total cholesterol: increased levels Patient monitoring☞ Check regularly for signs and symptoms of thromboembolic disease, especially dyspnea and chest pain. Patient teaching☞ Advise patient to immediately report signs and symptoms of thromboembolic disease and circulatory overload. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
|
| ? Mentioned in |
|---|
| Medical Dictionary |
| Free Tools: |
For surfers:
Free toolbar & extensions |
Word of the Day |
Help
For webmasters: Free content | Linking | Lookup box | Double-click lookup | Partner with us |
|---|