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anagrelide

   Also found in: Wikipedia 0.03 sec.
anagrelide /an·ag·re·lide/ (an-ag´rĕ-līd) an agent used to reduce elevated platelet counts and the risk of thrombosis in the treatment of hemorrhagic thrombocythemia; used as the hydrochloride salt.
Anagrelide
An orphan drug that is approved for treating PV patients on an investigational basis. Anagrelide works by controlling the level of platelets in the blood.
Mentioned in: Polycythemia Vera

anagrelide,
an antiplatelet agent.
indication This drug is prescribed for essential thrombocythemia.
contraindications Known hypersensitivity and hypotension prohibit its use.
adverse effects Life-threatening effects include congestive heart failure, myocardial infarction, myocardiopathy, cardiomegaly, complete heart block, atrial fibrillation, anemia, thrombocytopenia, ecchymosis, and lymphadenoma. Other serious effects include tachycardia, palpitations, arrhythmia, and seizures. Common side effects include orthostatic hypotension and rash.


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Anagrelide hydrochloride is marketed by Shire in the US and Canada under the trademark AGRYLIN(R) and will be marketed in Europe under the trademark XAGRID(R).
(Nasdaq: ELAB) announced today that it received final approval for Anagrelide HCl capsules, the generic equivalent of Agrylin(R)* capsules, in the same strengths as the brand, 0.
Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for anagrelide HCl capsules in 0.
 
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