Amycolatopsis


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Amycolatopsis

(am'ē-kō-la-top'sis),
A genus of gram-positive, filamentous bacteria, defined as a separate genus in 1986, which tends to break up into square fragments; recovered from soil and vegetable matter; Amycolatopsis is rare human pathogen that has been recovered from various clinical specimens, including spinal fluid. The type species is Amycolatopsis orientalis.
References in periodicals archive ?
In contrast to the studies on Amycolatopsis and fungal degradation of PLA, the reports on the bacterial degradation of PLA and the purification of the correlative enzyme from bacteria are relatively less.
Vancomycin is a branched tricyclic glycosylated nonribosomal peptide produced by the fermentation of Amycolatopsis orientalis, and it used in the treatment of infections caused by Gram-positive bacteria.
For example, a 5-dehydroxymethyl derivative of epoxyquinomicin C, isolated from Amycolatopsis has shown a significant growth inhibition in hormone-refractory PCA cell line DU-145 through the induction of a apoptotic cell death (Kikuchi et al.
In the vancomycin producer Amycolatopsis orientalis C329.
The posters are entitled "Genome Scanning Technology Reveals an Antibacterial Compound (ECO-0501) of a New Structural Class from the Vancomycin-Producer Amycolatopsis orientalis," "ECO-0501, a Novel Anti-Gram Positive Compound Defining a New Antibacterial Structural Class: Preclinical Evaluations" and "ECO-0501, a Novel Anti-Gram Positive Compound Defining a New Antibacterial Structural Class: Mechanistic Studies.