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ampakine
(redirected from Ampakines)

   Also found in: Wikipedia 0.01 sec.
ampakine
Neuropharmacology Any compound that facilitates synaptic transmission by binding to glutamate and enhance long-term potentiation, a critical component in long term memory, by enhancing the activity of AMPA receptor-rich neurons which enhance AMPA receptor activity by amplifying neural signals generated by glutamate binding; ampakines improve memory in early trials in Alzheimer's disease, schizophrenia See AMPA receptor, Long-term potentiation.


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  The Preventing Sleep Deprivation program, funded to the tune of $100 million, is exploring everything from the gene code of fruit flies—who can go for incredibly long periods without rest—to the use of ampakines, a novel class of chemicals thought to reverse the effects of sleep deprivation.
Studies of cells in the laboratory have shown that drugs called ampakines elevate production of BDNF.
Scientists in California are developing a class of experimental drugs call ampakines which flood the brain with a neurotransmitter that makes learning easy, improves memory and boosts alertness.
 
 
 
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