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ampakine
(redirected from Ampakines)

   Also found in: Wikipedia 0.01 sec.
ampakine
Neuropharmacology Any compound that facilitates synaptic transmission by binding to glutamate and enhance long-term potentiation, a critical component in long term memory, by enhancing the activity of AMPA receptor-rich neurons which enhance AMPA receptor activity by amplifying neural signals generated by glutamate binding; ampakines improve memory in early trials in Alzheimer's disease, schizophrenia See AMPA receptor, Long-term potentiation.


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The study is the first to show that ampakines can increase BDNF concentrations, the researchers say.
AMPAKINES are a new class of medication, which amplify the effects of glutamate, the primary excitatory neurotransmitter in the brain responsible for higher-order behaviors and cognitive activities, such as thinking, smelling, touching and memory.
 
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