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ampakine |
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ampakine Neuropharmacology Any compound that facilitates synaptic transmission by binding to glutamate and enhance long-term potentiation, a critical component in long term memory, by enhancing the activity of AMPA receptor-rich neurons which
enhance AMPA receptor activity by amplifying neural signals generated by glutamate binding; ampakines improve memory in early trials in Alzheimer's disease, schizophrenia See AMPA receptor, Long-term potentiation. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ? Mentioned in | ? References in periodicals archive | |
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| One ampakine is currently being
tested in people with Alzheimer's disease. It was invented at UC Irvine
- an ampakine compound trademarked as a pill under the name Ampalex. Gary Lynch at UC
Irvine using a high impact AMPAKINE drug, CX929, showed very encouraging
results in transgenic mice with the Huntington's Disease gene. |
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